Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment.
The lengthy treatment regimen for tuberculosis is necessary to eradicate a small sub-population of M. tuberculosis that persists in certain host locations under drug pressure. Limited information is available on persisting bacilli and their location within the lung during disease progression and aft...
Main Authors: | Donald R Hoff, Gavin J Ryan, Emily R Driver, Cornelius C Ssemakulu, Mary A De Groote, Randall J Basaraba, Anne J Lenaerts |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3061964?pdf=render |
Similar Items
-
Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach.
by: Gavin J Ryan, et al.
Published: (2010-06-01) -
Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis.
by: Gopinath S Palanisamy, et al.
Published: (2011-01-01) -
Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs.
by: Gopinath S Palanisamy, et al.
Published: (2012-01-01) -
Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis
by: Scott M. Irwin, et al.
Published: (2015-06-01) -
A model of type 2 diabetes in the guinea pig using sequential diet-induced glucose intolerance and streptozotocin treatment
by: Brendan K. Podell, et al.
Published: (2017-02-01)