Diagnostic intervention improved health-related quality of life among teenagers with food allergy.
<h4>Objectives</h4>The aim was to examine if a diagnostic intervention set up to assess current food allergy to cow's milk, hen's egg, fish, or wheat among teenagers had an impact on generic and disease specific health-related quality of life (HRQL). The study compared HRQL sco...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296664&type=printable |
| _version_ | 1797352499754041344 |
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| author | Linnéa Hedman Åsa Strinnholm Sven-Arne Jansson Anna Winberg |
| author_facet | Linnéa Hedman Åsa Strinnholm Sven-Arne Jansson Anna Winberg |
| author_sort | Linnéa Hedman |
| collection | DOAJ |
| description | <h4>Objectives</h4>The aim was to examine if a diagnostic intervention set up to assess current food allergy to cow's milk, hen's egg, fish, or wheat among teenagers had an impact on generic and disease specific health-related quality of life (HRQL). The study compared HRQL scoring before and two years after the intervention, and in relation to age matched controls without reported food allergy.<h4>Methods</h4>The study was performed within the Obstructive Lung Disease in Northern Sweden (OLIN) studies where a cohort study on asthma and allergic diseases among 8-year-old schoolchildren was initiated in 2006. At age 12 years, the 125/2612 (5%) children who reported allergy to cow's milk, hen's egg, fish, or wheat were invited to a diagnostic intervention including clinical examination, blood tests and evaluation by a pediatric allergist. Of 94 participants, 79 completed generic and disease specific HRQL questionnaires. Additionally, a random sample of 200 (62% of invited) children without food allergy from the OLIN cohort answered the generic HRQL questionnaire. The respondents of the HRQL questionnaires were re-examined two years later and 57 teenagers with and 154 without reported allergy participated.<h4>Results</h4>There were no significant differences in generic HRQL scores between teenagers with and without reported food allergy at study entry, or after the intervention. Among those with reported food allergy, we found a significant improvement in disease specific HRQL after the intervention (mean values: 3.41 vs 2.80, p<0.001). Teenagers with only food allergy had better disease specific HRQL compared to those with one, two or three concomitant allergic diseases, both before and after the intervention. Children with only food allergy significantly improved their HRQL after the intervention, 1.84 vs. 2.87 (p<0.001) but this association was not seen in children with one other allergic disorder (3.16 vs. 3.65, p = 0.121) or those with two or more allergic disorders (3.72 vs. 3.90, p = 0.148).<h4>Conclusion</h4>The diagnostic intervention showed a long-term improvement of disease specific HRQL but not generic HRQL. |
| first_indexed | 2024-03-08T13:16:26Z |
| format | Article |
| id | doaj.art-7e29456b15f448e1934c288d5a85d029 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-08T13:16:26Z |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-7e29456b15f448e1934c288d5a85d0292024-01-18T05:49:16ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01191e029666410.1371/journal.pone.0296664Diagnostic intervention improved health-related quality of life among teenagers with food allergy.Linnéa HedmanÅsa StrinnholmSven-Arne JanssonAnna Winberg<h4>Objectives</h4>The aim was to examine if a diagnostic intervention set up to assess current food allergy to cow's milk, hen's egg, fish, or wheat among teenagers had an impact on generic and disease specific health-related quality of life (HRQL). The study compared HRQL scoring before and two years after the intervention, and in relation to age matched controls without reported food allergy.<h4>Methods</h4>The study was performed within the Obstructive Lung Disease in Northern Sweden (OLIN) studies where a cohort study on asthma and allergic diseases among 8-year-old schoolchildren was initiated in 2006. At age 12 years, the 125/2612 (5%) children who reported allergy to cow's milk, hen's egg, fish, or wheat were invited to a diagnostic intervention including clinical examination, blood tests and evaluation by a pediatric allergist. Of 94 participants, 79 completed generic and disease specific HRQL questionnaires. Additionally, a random sample of 200 (62% of invited) children without food allergy from the OLIN cohort answered the generic HRQL questionnaire. The respondents of the HRQL questionnaires were re-examined two years later and 57 teenagers with and 154 without reported allergy participated.<h4>Results</h4>There were no significant differences in generic HRQL scores between teenagers with and without reported food allergy at study entry, or after the intervention. Among those with reported food allergy, we found a significant improvement in disease specific HRQL after the intervention (mean values: 3.41 vs 2.80, p<0.001). Teenagers with only food allergy had better disease specific HRQL compared to those with one, two or three concomitant allergic diseases, both before and after the intervention. Children with only food allergy significantly improved their HRQL after the intervention, 1.84 vs. 2.87 (p<0.001) but this association was not seen in children with one other allergic disorder (3.16 vs. 3.65, p = 0.121) or those with two or more allergic disorders (3.72 vs. 3.90, p = 0.148).<h4>Conclusion</h4>The diagnostic intervention showed a long-term improvement of disease specific HRQL but not generic HRQL.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296664&type=printable |
| spellingShingle | Linnéa Hedman Åsa Strinnholm Sven-Arne Jansson Anna Winberg Diagnostic intervention improved health-related quality of life among teenagers with food allergy. PLoS ONE |
| title | Diagnostic intervention improved health-related quality of life among teenagers with food allergy. |
| title_full | Diagnostic intervention improved health-related quality of life among teenagers with food allergy. |
| title_fullStr | Diagnostic intervention improved health-related quality of life among teenagers with food allergy. |
| title_full_unstemmed | Diagnostic intervention improved health-related quality of life among teenagers with food allergy. |
| title_short | Diagnostic intervention improved health-related quality of life among teenagers with food allergy. |
| title_sort | diagnostic intervention improved health related quality of life among teenagers with food allergy |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296664&type=printable |
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