Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review

The long-term administration of vancomycin has increased; however, the pulmonary adverse reactions of long-term vancomycin treatment remain under-studied. A 75-year-old male patient with vertebral osteomyelitis receiving long-term vancomycin therapy developed a fever. High resolution computed tomogr...

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Main Authors: Young-Shin Lee, Yu-Mi Lee
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/57/6/610
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author Young-Shin Lee
Yu-Mi Lee
author_facet Young-Shin Lee
Yu-Mi Lee
author_sort Young-Shin Lee
collection DOAJ
description The long-term administration of vancomycin has increased; however, the pulmonary adverse reactions of long-term vancomycin treatment remain under-studied. A 75-year-old male patient with vertebral osteomyelitis receiving long-term vancomycin therapy developed a fever. High resolution computed tomography showed irregular ground glass opacity and consolidation in the right upper lung. The patient developed organizing pneumonia. This occurred without peripheral eosinophilia or adverse reactions in the skin and liver. The administration of vancomycin was discontinued. He recovered from organizing pneumonia after four weeks of steroid therapy. Solitary organizing pneumonia can develop during treatment with vancomycin. When pulmonary inflammation occurs and other causes of pneumonia are excluded, vancomycin therapy should be discontinued.
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spelling doaj.art-7e2aac74142a485c9d28785c748f64602023-11-21T23:48:01ZengMDPI AGMedicina1010-660X1648-91442021-06-0157661010.3390/medicina57060610Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature ReviewYoung-Shin Lee0Yu-Mi Lee1Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, 23, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, KoreaDivision of Infectious Diseases, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, 23, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, KoreaThe long-term administration of vancomycin has increased; however, the pulmonary adverse reactions of long-term vancomycin treatment remain under-studied. A 75-year-old male patient with vertebral osteomyelitis receiving long-term vancomycin therapy developed a fever. High resolution computed tomography showed irregular ground glass opacity and consolidation in the right upper lung. The patient developed organizing pneumonia. This occurred without peripheral eosinophilia or adverse reactions in the skin and liver. The administration of vancomycin was discontinued. He recovered from organizing pneumonia after four weeks of steroid therapy. Solitary organizing pneumonia can develop during treatment with vancomycin. When pulmonary inflammation occurs and other causes of pneumonia are excluded, vancomycin therapy should be discontinued.https://www.mdpi.com/1648-9144/57/6/610organizing pneumoniapneumonitisvancomycin
spellingShingle Young-Shin Lee
Yu-Mi Lee
Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review
Medicina
organizing pneumonia
pneumonitis
vancomycin
title Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review
title_full Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review
title_fullStr Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review
title_full_unstemmed Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review
title_short Vancomycin-Induced Organizing Pneumonia: A Case Report and Literature Review
title_sort vancomycin induced organizing pneumonia a case report and literature review
topic organizing pneumonia
pneumonitis
vancomycin
url https://www.mdpi.com/1648-9144/57/6/610
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