Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors

Immunosuppression is a typical hallmark of cancer and frequently includes perturbations of the NKG2D tumor recognition system as well as impaired signaling by other activating NK cell receptors. Several in vitro studies suggested that sustained engagement of the NKG2D receptor, as it is occurring in...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Christine Koch, Younghoon Kim, Tobias Zöller, Christina Born, Alexander Steinle
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Frontiers Media S.A. 2017-11-01
Σειρά:Frontiers in Immunology
Θέματα:
Διαθέσιμο Online:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01466/full