Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon
The term “collision tumor” is described as the coexistence of two or more histologically distinct neoplastic morphologies separated by normal tissue in the same organ. Collision phenomenon involving two and more neoplasms of the thyroid gland is a rare entity. A 54 year old female presented with a d...
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| Format: | Article |
| Language: | English |
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Light House Polyclinic Mangalore
2023-11-01
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| Series: | Online Journal of Health & Allied Sciences |
| Subjects: | |
| Online Access: | https://www.ojhas.org/issue87/2023-3-12.html |
| _version_ | 1827356798381719552 |
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| author | Gopikrishnan Vijayakumar Anand Vijaya Narayanan Sithara Aravind Sandeep Vijay P |
| author_facet | Gopikrishnan Vijayakumar Anand Vijaya Narayanan Sithara Aravind Sandeep Vijay P |
| author_sort | Gopikrishnan Vijayakumar |
| collection | DOAJ |
| description | The term “collision tumor” is described as the coexistence of two or more histologically distinct neoplastic morphologies separated by normal tissue in the same organ. Collision phenomenon involving two and more neoplasms of the thyroid gland is a rare entity. A 54 year old female presented with a diffuse large swelling of thyroid gland increasing in size over a period of 20 years. Clinicoradiological examination reveal heterogenous enhancing lesion involving bilateral neck up to skull base. Patient underwent total thyroidectomy with central compartment clearance and bilateral selective neck node dissections. On histopathology, collision tumors with components of five histologically different entities were identified, including hurtle cell adenoma, well differentiated tumor of uncertain malignant potential, papillary thyroid carcinoma-classical variant, follicular variant of papillary thyroid carcinoma and primary squamous cell carcinoma of thyroid within different lobes of thyroid. To the best of our knowledge, this is the first documentation of a collision tumor with five histologically different entities within a single thyroid gland. |
| first_indexed | 2024-03-08T05:15:11Z |
| format | Article |
| id | doaj.art-7e2aed1cd24c4a4a82924532f8dd918f |
| institution | Directory Open Access Journal |
| issn | 0972-5997 |
| language | English |
| last_indexed | 2024-03-08T05:15:11Z |
| publishDate | 2023-11-01 |
| publisher | Light House Polyclinic Mangalore |
| record_format | Article |
| series | Online Journal of Health & Allied Sciences |
| spelling | doaj.art-7e2aed1cd24c4a4a82924532f8dd918f2024-02-07T04:20:59ZengLight House Polyclinic MangaloreOnline Journal of Health & Allied Sciences0972-59972023-11-01223Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision PhenomenonGopikrishnan Vijayakumar0Anand Vijaya Narayanan1Sithara Aravind2Sandeep Vijay P3Fellow in Head and Neck Pathology, Department of Oncopathology, CLSTR, Malabar Cancer Centre, Thalassery, Kerala, India.Assistant Professor, Department of Oncopathology, CLSTR, Malabar Cancer Centre, Thalassery, Kerala, India.Associate Professor, Department of Oncopathology, CLSTR, Malabar Cancer Centre, Thalassery, Kerala, India.Assistant Professor, Department of Surgical Oncology, Malabar Cancer Centre, Thalassery, Kerala, India.The term “collision tumor” is described as the coexistence of two or more histologically distinct neoplastic morphologies separated by normal tissue in the same organ. Collision phenomenon involving two and more neoplasms of the thyroid gland is a rare entity. A 54 year old female presented with a diffuse large swelling of thyroid gland increasing in size over a period of 20 years. Clinicoradiological examination reveal heterogenous enhancing lesion involving bilateral neck up to skull base. Patient underwent total thyroidectomy with central compartment clearance and bilateral selective neck node dissections. On histopathology, collision tumors with components of five histologically different entities were identified, including hurtle cell adenoma, well differentiated tumor of uncertain malignant potential, papillary thyroid carcinoma-classical variant, follicular variant of papillary thyroid carcinoma and primary squamous cell carcinoma of thyroid within different lobes of thyroid. To the best of our knowledge, this is the first documentation of a collision tumor with five histologically different entities within a single thyroid gland.https://www.ojhas.org/issue87/2023-3-12.htmlcollision tumorsfollicular variant of papillary thyroid carcinomahurtle cell adenomaprimary squamous cell carcinomapapillary thyroid carcinomawell-differentiated tumour of uncertain malignant potential |
| spellingShingle | Gopikrishnan Vijayakumar Anand Vijaya Narayanan Sithara Aravind Sandeep Vijay P Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon Online Journal of Health & Allied Sciences collision tumors follicular variant of papillary thyroid carcinoma hurtle cell adenoma primary squamous cell carcinoma papillary thyroid carcinoma well-differentiated tumour of uncertain malignant potential |
| title | Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon |
| title_full | Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon |
| title_fullStr | Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon |
| title_full_unstemmed | Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon |
| title_short | Primary Squamous Cell Carcinoma with Thyroid Collision Tumors: A Case Report of Rare Thyroid Collision Phenomenon |
| title_sort | primary squamous cell carcinoma with thyroid collision tumors a case report of rare thyroid collision phenomenon |
| topic | collision tumors follicular variant of papillary thyroid carcinoma hurtle cell adenoma primary squamous cell carcinoma papillary thyroid carcinoma well-differentiated tumour of uncertain malignant potential |
| url | https://www.ojhas.org/issue87/2023-3-12.html |
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