Measurement of Pulsatile Insulin Secretion: Rationale and Methodology

Measurement of Pulsatile Insulin Secretion: Rationale and Methodology

Pancreatic β-cells are responsible for the synthesis and exocytosis of insulin in response to an increase in circulating glucose. Insulin secretion occurs in a pulsatile manner, with oscillatory pulses superimposed on a basal secretion rate. Insulin pulses are a marker of β-cell health, and secretor...

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Bibliographic Details
Main Authors:	Marcello C. Laurenti, Aleksey Matveyenko, Adrian Vella
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Metabolites
Subjects:	insulin pulses C-peptide kinetics hormone deconvolution pulsatile insulin secretion
Online Access:	https://www.mdpi.com/2218-1989/11/7/409

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