The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension

Objective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women  with chronic hypertension. Results:  a relative risk of preeclampsia among methyldopa grou...

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Main Authors: Masoumeh Ghafarzadeh, Amir Shakarami, Fatemeh Yari, Parsa Namdari
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Hypertension in Pregnancy
Subjects:
Online Access:http://dx.doi.org/10.1080/10641955.2020.1766489
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author Masoumeh Ghafarzadeh
Amir Shakarami
Fatemeh Yari
Parsa Namdari
author_facet Masoumeh Ghafarzadeh
Amir Shakarami
Fatemeh Yari
Parsa Namdari
author_sort Masoumeh Ghafarzadeh
collection DOAJ
description Objective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women  with chronic hypertension. Results:  a relative risk of preeclampsia among methyldopa group was 3.45 times higher than the metoprolol, the relative risk of preterm labor was not significantly between methyldopa and metoprolol group, LBW, and IUGR in methyldopa and amlodipine groups . Conclusion Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension.the incidence of preeclampsia was greater in methyldopa group.
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spelling doaj.art-7e3076facd8745d69314a445d07d4fa72023-09-19T09:24:43ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652020-07-0139331431810.1080/10641955.2020.17664891766489The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertensionMasoumeh Ghafarzadeh0Amir Shakarami1Fatemeh Yari2Parsa Namdari3School of Medicine, Lorestan University of Medical SciencesSchool of Medicine, Lorestan University of Medical SciencesLorestan University of Medical SciencesUniversity of DebrecenObjective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women  with chronic hypertension. Results:  a relative risk of preeclampsia among methyldopa group was 3.45 times higher than the metoprolol, the relative risk of preterm labor was not significantly between methyldopa and metoprolol group, LBW, and IUGR in methyldopa and amlodipine groups . Conclusion Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension.the incidence of preeclampsia was greater in methyldopa group.http://dx.doi.org/10.1080/10641955.2020.1766489pregnancychronic hypertensionmetoprololmethyldopaadverse drug effectsmaternal outcomesfetal and neonatal outcomes
spellingShingle Masoumeh Ghafarzadeh
Amir Shakarami
Fatemeh Yari
Parsa Namdari
The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
Hypertension in Pregnancy
pregnancy
chronic hypertension
metoprolol
methyldopa
adverse drug effects
maternal outcomes
fetal and neonatal outcomes
title The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
title_full The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
title_fullStr The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
title_full_unstemmed The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
title_short The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
title_sort comparison of side effects of methyldopa amlodipine and metoprolol in pregnant women with chronic hypertension
topic pregnancy
chronic hypertension
metoprolol
methyldopa
adverse drug effects
maternal outcomes
fetal and neonatal outcomes
url http://dx.doi.org/10.1080/10641955.2020.1766489
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