The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension
Objective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women with chronic hypertension. Results: a relative risk of preeclampsia among methyldopa grou...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2020-07-01
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Series: | Hypertension in Pregnancy |
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Online Access: | http://dx.doi.org/10.1080/10641955.2020.1766489 |
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author | Masoumeh Ghafarzadeh Amir Shakarami Fatemeh Yari Parsa Namdari |
author_facet | Masoumeh Ghafarzadeh Amir Shakarami Fatemeh Yari Parsa Namdari |
author_sort | Masoumeh Ghafarzadeh |
collection | DOAJ |
description | Objective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women with chronic hypertension. Results: a relative risk of preeclampsia among methyldopa group was 3.45 times higher than the metoprolol, the relative risk of preterm labor was not significantly between methyldopa and metoprolol group, LBW, and IUGR in methyldopa and amlodipine groups . Conclusion Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension.the incidence of preeclampsia was greater in methyldopa group. |
first_indexed | 2024-03-11T23:47:09Z |
format | Article |
id | doaj.art-7e3076facd8745d69314a445d07d4fa7 |
institution | Directory Open Access Journal |
issn | 1064-1955 1525-6065 |
language | English |
last_indexed | 2024-03-11T23:47:09Z |
publishDate | 2020-07-01 |
publisher | Taylor & Francis Group |
record_format | Article |
series | Hypertension in Pregnancy |
spelling | doaj.art-7e3076facd8745d69314a445d07d4fa72023-09-19T09:24:43ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652020-07-0139331431810.1080/10641955.2020.17664891766489The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertensionMasoumeh Ghafarzadeh0Amir Shakarami1Fatemeh Yari2Parsa Namdari3School of Medicine, Lorestan University of Medical SciencesSchool of Medicine, Lorestan University of Medical SciencesLorestan University of Medical SciencesUniversity of DebrecenObjective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women with chronic hypertension. Results: a relative risk of preeclampsia among methyldopa group was 3.45 times higher than the metoprolol, the relative risk of preterm labor was not significantly between methyldopa and metoprolol group, LBW, and IUGR in methyldopa and amlodipine groups . Conclusion Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension.the incidence of preeclampsia was greater in methyldopa group.http://dx.doi.org/10.1080/10641955.2020.1766489pregnancychronic hypertensionmetoprololmethyldopaadverse drug effectsmaternal outcomesfetal and neonatal outcomes |
spellingShingle | Masoumeh Ghafarzadeh Amir Shakarami Fatemeh Yari Parsa Namdari The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension Hypertension in Pregnancy pregnancy chronic hypertension metoprolol methyldopa adverse drug effects maternal outcomes fetal and neonatal outcomes |
title | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension |
title_full | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension |
title_fullStr | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension |
title_full_unstemmed | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension |
title_short | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension |
title_sort | comparison of side effects of methyldopa amlodipine and metoprolol in pregnant women with chronic hypertension |
topic | pregnancy chronic hypertension metoprolol methyldopa adverse drug effects maternal outcomes fetal and neonatal outcomes |
url | http://dx.doi.org/10.1080/10641955.2020.1766489 |
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