Pooled post hoc analysis of population pharmacokinetics of oxycodone and acetaminophen following a single oral dose of biphasic immediate-release/extended-release oxycodone/acetaminophen tablets

Pooled post hoc analysis of population pharmacokinetics of oxycodone and acetaminophen following a single oral dose of biphasic immediate-release/extended-release oxycodone/acetaminophen tablets

Ryan M Franke, Terri Morton, Krishna Devarakonda Department of Clinical Pharmacology, Mallinckrodt Pharmaceuticals, Hazelwood, MO, USA Abstract: This analysis evaluated the single-dose population pharmacokinetics (PK) of biphasic immediate-release (IR)/extended-release (ER) oxycodone (OC)/acetamin...

Full description

Bibliographic Details
Main Authors:	Franke RM, Morton T, Devarakonda K
Format:	Article
Language:	English
Published:	Dove Medical Press 2015-08-01
Series:	Drug Design, Development and Therapy
Online Access:	http://www.dovepress.com/pooled-post-hoc-analysis-of-population-pharmacokinetics-of-oxycodone-a-peer-reviewed-article-DDDT

Similar Items

Profile of extended-release oxycodone/acetaminophen for acute pain
by: Bekhit MH
Published: (2015-10-01)

Single- and multiple-dose pharmacokinetics of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) compared with immediate-release hydrocodone bitartrate/ibuprofen and immediate-release tramadol HCl/acetaminophen
by: Devarakonda K, et al.
Published: (2015-09-01)

Comparison of single-dose and multiple-dose pharmacokinetics between two formulations of hydrocodone bitartrate/acetaminophen: immediate-release versus biphasic immediate- release/extended release
by: Devarakonda K, et al.
Published: (2015-09-01)

Pharmacokinetics and bioavailability of oxycodone and acetaminophen following single-dose administration of MNK-795, a dual-layer biphasic IR/ER combination formulation, under fed and fasted conditions
by: Devarakonda K, et al.
Published: (2014-08-01)

Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults
by: Gaskell, H, et al.
Published: (2009)

Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults.
by: Gaskell, H, et al.
Published: (2009)

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study
by: Wei Lu, et al.
Published: (2018-06-01)

Development of controlled release bi-layered tablets containing oxycodone hydrochloride
by: Kyung Hun Kim, et al.
Published: (2016-02-01)

Effects of aprepitant on the pharmacokinetics of controlled-release oral oxycodone in cancer patients.
by: Yutaka Fujiwara, et al.
Published: (2014-01-01)

Design and in vivo evaluation of oxycodone once-a-day controlled-release tablets
by: Kim JY, et al.
Published: (2015-01-01)

Abuse-deterrent extended-release oxycodone and risk of opioid-related harm
by: Paljarvi, T, et al.
Published: (2021)

Evaluation of the effect of managing oxycodone/acetaminophen as a psychotropic medicine: An interrupted time-series study
by: Cheng Xiang, et al.
Published: (2023-03-01)

Endoscopic removal of slow release oxycodone tablets in a case of voluntary acute poisoning
by: Sossio Serra, et al.
Published: (2021-03-01)

Oxycodone hydrochloride immediate-release analgesic for managing severe pain: abuse-deterrent formulations
by: Kibbe AH, et al.
Published: (2018-04-01)

Oxycodone/Acetaminophen: The Tailoring Combination Treatment for Specific Clinical Profile of Opioid Well-Responsive Cancer Pain
by: De Santis S, et al.
Published: (2021-02-01)

Efficacy and safety of controlled-release oxycodone/naloxone versus controlled-release oxycodone in Korean patients with cancer-related pain: a randomized controlled trial
by: Kyung-Hee Lee, et al.
Published: (2017-09-01)

Developments in managing severe chronic pain: role of oxycodone–naloxone extended release
by: Fanelli G, et al.
Published: (2015-07-01)

Combatting pain after orthopedic/trauma surgery- perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone
by: Gertrud Haeseler, et al.
Published: (2017-07-01)

Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats.
by: Marco Pravetoni, et al.
Published: (2014-01-01)

Pain treatment with high-dose, controlled-release oxycodone: an Italian perspective
by: Fabio Ferrarese, et al.
Published: (2008-09-01)

Analgesic efficacy, safety, and tolerability of a long-acting abuse-deterrent formulation of oxycodone for moderate-to-severe chronic low back pain in subjects successfully switched from immediate-release oxycodone
by: Markman J, et al.
Published: (2018-09-01)

ENhANCE trial protocol: A multi-centre, randomised, phase IV trial comparing the efficacy of oxycodone/naloxone prolonged release (OXN PR) versus oxycodone prolonged release (Oxy PR) tablets in patients with advanced cancer
by: Aaron K. Wong, et al.
Published: (2022-12-01)

Comparison of immediate release oral oxycodone hydrochloride(kappa 2 receptor agonist) with oral pantoprazole in the treatment of functional dyspepsia
by: Omar, Azaharim
Published: (2012)

Comparison of immediate release oral oxycodone hydrochloride(kappa 2 receptor agonist) with oral pantoprazole in the treatment of functional dyspepsia
by: Omar, Azaharim
Published: (2012)

Oxycodone in mastectomy surgery
by: Putu Pramana Suarjaya, et al.
Published: (2020-01-01)

Population Pharmacokinetics of Oxycodone and Metabolites in Patients with Cancer-Related Pain
by: Bram C. Agema, et al.
Published: (2021-06-01)

Curative effect of oxycodone sustained-release tablets combined with duloxetine versus paroxetine in treatment of depression and pain from advanced cancer
by: ZENG Yuan, et al.
Published: (2020-10-01)

Efficacy of acetaminophen with and without oxycodone for analgesia in non-operative treatment of extremity fractures in adults: protocol for a double-blind randomized clinical trial
by: Tao Gao, et al.
Published: (2019-08-01)

Oxycodone, an opioid like the others?
by: Nicolas Marie, et al.
Published: (2023-12-01)

Epidural Oxycodone for Acute Pain
by: Panu Piirainen, et al.
Published: (2022-05-01)

The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism
by: Qi Zhou, et al.
Published: (2023-12-01)

A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief)
by: Inoue S, et al.
Published: (2017-08-01)

CLONIDINE INHIBITS OXYCODONE-MOTIVATED BEHAVIORS, BRAIN STIMULATION REWARD AND POTENTIATES THE ANTINOCICEPTIVE EFFECTS OF OXYCODONE IN RODENTS
by: Ashton Taylor, et al.
Published: (2023-10-01)

Effects of sex and estrous cycle on intravenous oxycodone self-administration and the reinstatement of oxycodone-seeking behavior in rats
by: Nicole M. Hinds, et al.
Published: (2023-07-01)

Comparison on the efficacy of immediate release oxycodone and tramadol in reducing postoperative pain, nausea and vomiting in post laparotomy patients weaned from PCA morphine
by: Kumar, Shyamala a/p V.
Published: (2016)

Particle size affects pharmacokinetics of milled oxycodone hydrochloride tablet products following nasal insufflation in nondependent, recreational opioid users
by: Saeid Raofi, et al.
Published: (2021-09-01)

Tramadol Steady-State Pharmacokinetics of Immediate-Release Capsules and Sustained-Release Tablets in Dogs
by: Esther Winter, et al.
Published: (2022-12-01)

Managing severe pain and abuse potential: the potential impact of a new abuse-deterrent formulation oxycodone/naltrexone extended-release product
by: Pergolizzi, J, et al.
Published: (2018-02-01)

Meta-analysis of efficacy and safety of sustained release oxycodone hydrochloride rectal administration for moderate to severe pain
by: Xian Bing Hou, et al.
Published: (2022-01-01)

Safety and tolerability of controlled-release oxycodone on postoperative pain in patients submitted to the oncologic head and neck surgery
by: Ismar Lima Cavalcanti, et al.