Programming Hippocampal Neural Stem/Progenitor Cells into Oligodendrocytes Enhances Remyelination in the Adult Brain after Injury
Demyelinating diseases are characterized by a loss of oligodendrocytes leading to axonal degeneration and impaired brain function. Current strategies used for the treatment of demyelinating disease such as multiple sclerosis largely rely on modulation of the immune system. Only limited treatment opt...
Main Authors: | Simon M.G. Braun, Gregor-Alexander Pilz, Raquel A.C. Machado, Jonathan Moss, Burkhard Becher, Nicolas Toni, Sebastian Jessberger |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715005501 |
Similar Items
-
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
by: Alerie Guzman De La Fuente, et al.
Published: (2017-08-01) -
Neural stem cells and oligodendrocyte progenitor cells compete for remyelination in the corpus callosum
by: Sarah Moyon, et al.
Published: (2023-01-01) -
OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease
by: Wonjin Yun, et al.
Published: (2022-01-01) -
PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation.
by: Jens O Watzlawik, et al.
Published: (2013-01-01) -
The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies
by: Adriana Octaviana Dulamea
Published: (2017-01-01)