Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis
Introduction: The use of early screening questionnaires for chronic obstructive pulmonary disease (COPD) in primary health care could improve underdiagnosis. Several instruments are currently available, but there is scant information on their diagnostic performance. Objective: To determine the vali...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Colombia
2021-03-01
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| Series: | Revista de la Facultad de Medicina |
| Subjects: | |
| Online Access: | https://revistas.unal.edu.co/index.php/revfacmed/article/view/88706 |
| _version_ | 1797824716176621568 |
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| author | Alirio Rodrigo Bastidas-Goyes Andrés Orlando Cardozo-Niño Elías Quintero-Muñoz Kenny Andrés López-Gómez Lilia Patricia Suárez-Escobar Lorena Esmeralda Hernández-Santos |
| author_facet | Alirio Rodrigo Bastidas-Goyes Andrés Orlando Cardozo-Niño Elías Quintero-Muñoz Kenny Andrés López-Gómez Lilia Patricia Suárez-Escobar Lorena Esmeralda Hernández-Santos |
| author_sort | Alirio Rodrigo Bastidas-Goyes |
| collection | DOAJ |
| description | Introduction: The use of early screening questionnaires for chronic obstructive pulmonary disease (COPD) in primary health care could improve underdiagnosis. Several instruments are currently available, but there is scant information on their diagnostic performance.
Objective: To determine the validity of different questionnaires for COPD diagnosis.
Materials and methods: A systematic review and a meta-analysis of diagnostic test accuracy were carried out. A search of the literature published between July 1, 1997, and June 30, 2019 was performed in PubMed, EMBASE, and LILACS databases using MeSH and DeCS terms and the PICO strategy. Based on the inclusion and exclusion criteria, two reviewers selected the articles for complete analysis. Article quality was assessed using the QUADAS instrument.
Results: 19 articles were included for analysis. Overall results were: sensitivity: 68.1% (95%CI: 66.7% -69.4%); specificity: 64.9% (95%CI: 64.3-65.5); positive likelihood ratio: 2.024 (95%CI: 1.715-2.388); negative likelihood ratio: 0.407 (95%CI: 0.289-0.573); and receiver operating characteristic area under the curve (ROC AUC): 0.75. The COPD-PS questionnaire reported the highest performance with sensitivity of 0.673 (95%CI: 0.653-0.692), specificity of 0.663 (95%CI: 0.65.5- 0.651), and ROC AUC of 0.750. It was followed by LFQ with sensitivity of 0.840 (95%CI: 0.806-0.871), specificity of 0.312 (95%CI: 0.289-0.336), and ROC AUC of 0.730. Finally, CDQ had sensitivity of 0.798 (95%CI: 0.764-0.829), specificity of 0.517 (95%CI: 0.495-0.538), and ROC AUC of 0.727.
Conclusion: Clinical prediction instruments for COPD diagnosis have an acceptable performance. The COPD-PS, LFQ and CDQ questionnaires show a similar performance.
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| first_indexed | 2024-03-13T10:43:17Z |
| format | Article |
| id | doaj.art-7e314775f9a34638abcebd19f93c1c8d |
| institution | Directory Open Access Journal |
| issn | 0120-0011 2357-3848 |
| language | English |
| last_indexed | 2024-03-13T10:43:17Z |
| publishDate | 2021-03-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Revista de la Facultad de Medicina |
| spelling | doaj.art-7e314775f9a34638abcebd19f93c1c8d2023-05-17T22:03:32ZengUniversidad Nacional de ColombiaRevista de la Facultad de Medicina0120-00112357-38482021-03-0169110.15446/revfacmed.v69n1.88706Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysisAlirio Rodrigo Bastidas-Goyes0Andrés Orlando Cardozo-Niño1Elías Quintero-Muñoz2Kenny Andrés López-Gómez3Lilia Patricia Suárez-Escobar4Lorena Esmeralda Hernández-Santos5Universidad de La Sabana - Faculty of Medicine - Department of Internal Medicine - Chía - Colombia.Universidad de La Sabana - Faculty of Medicine - Department of Internal Medicine - Internal Medicine Residency Program - Chía - Colombia.Universidad de La Sabana - Faculty of Medicine - Department of Internal Medicine - Internal Medicine Residency Program - Chía - Colombia.Universidad de La Sabana - Faculty of Medicine - Chía - Colombia.Universidad de La Sabana - Faculty of Medicine - Chía - Colombia.Universidad de La Sabana - Faculty of Medicine - Chía - Colombia.Introduction: The use of early screening questionnaires for chronic obstructive pulmonary disease (COPD) in primary health care could improve underdiagnosis. Several instruments are currently available, but there is scant information on their diagnostic performance. Objective: To determine the validity of different questionnaires for COPD diagnosis. Materials and methods: A systematic review and a meta-analysis of diagnostic test accuracy were carried out. A search of the literature published between July 1, 1997, and June 30, 2019 was performed in PubMed, EMBASE, and LILACS databases using MeSH and DeCS terms and the PICO strategy. Based on the inclusion and exclusion criteria, two reviewers selected the articles for complete analysis. Article quality was assessed using the QUADAS instrument. Results: 19 articles were included for analysis. Overall results were: sensitivity: 68.1% (95%CI: 66.7% -69.4%); specificity: 64.9% (95%CI: 64.3-65.5); positive likelihood ratio: 2.024 (95%CI: 1.715-2.388); negative likelihood ratio: 0.407 (95%CI: 0.289-0.573); and receiver operating characteristic area under the curve (ROC AUC): 0.75. The COPD-PS questionnaire reported the highest performance with sensitivity of 0.673 (95%CI: 0.653-0.692), specificity of 0.663 (95%CI: 0.65.5- 0.651), and ROC AUC of 0.750. It was followed by LFQ with sensitivity of 0.840 (95%CI: 0.806-0.871), specificity of 0.312 (95%CI: 0.289-0.336), and ROC AUC of 0.730. Finally, CDQ had sensitivity of 0.798 (95%CI: 0.764-0.829), specificity of 0.517 (95%CI: 0.495-0.538), and ROC AUC of 0.727. Conclusion: Clinical prediction instruments for COPD diagnosis have an acceptable performance. The COPD-PS, LFQ and CDQ questionnaires show a similar performance. https://revistas.unal.edu.co/index.php/revfacmed/article/view/88706Chronic Obstructive Pulmonary DiseaseSurveys and QuestionnairesReproducibility of Results |
| spellingShingle | Alirio Rodrigo Bastidas-Goyes Andrés Orlando Cardozo-Niño Elías Quintero-Muñoz Kenny Andrés López-Gómez Lilia Patricia Suárez-Escobar Lorena Esmeralda Hernández-Santos Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis Revista de la Facultad de Medicina Chronic Obstructive Pulmonary Disease Surveys and Questionnaires Reproducibility of Results |
| title | Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis |
| title_full | Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis |
| title_fullStr | Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis |
| title_full_unstemmed | Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis |
| title_short | Clinical questionnaires for chronic obstructive pulmonary disease diagnosis: A systematic review and meta-analysis |
| title_sort | clinical questionnaires for chronic obstructive pulmonary disease diagnosis a systematic review and meta analysis |
| topic | Chronic Obstructive Pulmonary Disease Surveys and Questionnaires Reproducibility of Results |
| url | https://revistas.unal.edu.co/index.php/revfacmed/article/view/88706 |
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