Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.

PURPOSE: To determine by objective methods the minimum number of spectral-domain optical coherence tomographic (SD-OCT) images to average to obtain the clearest retinal image. METHODS: SD-OCT Images were obtained from 9 healthy eyes and also from a phantom eye model. The SD-OCT images were obtained...

Full description

Bibliographic Details
Main Authors: Makoto Shirasawa, Taiji Sakamoto, Hiroto Terasaki, Takehiro Yamashita, Eisuke Uchino, Shozo Sonoda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206300?pdf=render
_version_ 1819195669374566400
author Makoto Shirasawa
Taiji Sakamoto
Hiroto Terasaki
Takehiro Yamashita
Eisuke Uchino
Shozo Sonoda
author_facet Makoto Shirasawa
Taiji Sakamoto
Hiroto Terasaki
Takehiro Yamashita
Eisuke Uchino
Shozo Sonoda
author_sort Makoto Shirasawa
collection DOAJ
description PURPOSE: To determine by objective methods the minimum number of spectral-domain optical coherence tomographic (SD-OCT) images to average to obtain the clearest retinal image. METHODS: SD-OCT Images were obtained from 9 healthy eyes and also from a phantom eye model. The SD-OCT images were obtained by averaging 1, 5, 20, 60, and 100 B-scan images. The reflectivity (mean gray value) of the different retinal layers was evaluated in these images. The image quality was evaluated by the size of the standard deviations (SDs) and the contrast-to-noise ratios (CNRs). A phantom eye model made by TiO2 silicone plates was also examined. RESULTS: The SDs decreased significantly when the number of images averaged increased from 1 to 5 and also from 5 to 20 (P<0.05, post hoc Tukey's honestly significant difference tests). The SD of the automatic real time averaging of 1 (ART = 1) and ART = 5 were significantly larger than the SD of ART = 100 (P<0.05). The SDs of all other averaged numbers were not significantly larger than that of ART = 100. The CNR increased with an increase in the number of images averaged, and there was a significant increase between ART = 1 to 5 and between ART = 5 to 20 (P<0.05). No significant differences in the CNR was observed between ART = 5, ART = 20 and ART = 60. Similar results were obtained with the phantom eye model. CONCLUSIONS: Although the image quality of the SD-OCT images of the retina improved with an increase in the number of images averaged, it does not improve significantly by averaging more than 20 images.
first_indexed 2024-12-23T02:16:26Z
format Article
id doaj.art-7e3230d3e91049938017a060e6743f74
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-12-23T02:16:26Z
publishDate 2014-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-7e3230d3e91049938017a060e6743f742022-12-21T18:03:39ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01910e11055010.1371/journal.pone.0110550Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.Makoto ShirasawaTaiji SakamotoHiroto TerasakiTakehiro YamashitaEisuke UchinoShozo SonodaPURPOSE: To determine by objective methods the minimum number of spectral-domain optical coherence tomographic (SD-OCT) images to average to obtain the clearest retinal image. METHODS: SD-OCT Images were obtained from 9 healthy eyes and also from a phantom eye model. The SD-OCT images were obtained by averaging 1, 5, 20, 60, and 100 B-scan images. The reflectivity (mean gray value) of the different retinal layers was evaluated in these images. The image quality was evaluated by the size of the standard deviations (SDs) and the contrast-to-noise ratios (CNRs). A phantom eye model made by TiO2 silicone plates was also examined. RESULTS: The SDs decreased significantly when the number of images averaged increased from 1 to 5 and also from 5 to 20 (P<0.05, post hoc Tukey's honestly significant difference tests). The SD of the automatic real time averaging of 1 (ART = 1) and ART = 5 were significantly larger than the SD of ART = 100 (P<0.05). The SDs of all other averaged numbers were not significantly larger than that of ART = 100. The CNR increased with an increase in the number of images averaged, and there was a significant increase between ART = 1 to 5 and between ART = 5 to 20 (P<0.05). No significant differences in the CNR was observed between ART = 5, ART = 20 and ART = 60. Similar results were obtained with the phantom eye model. CONCLUSIONS: Although the image quality of the SD-OCT images of the retina improved with an increase in the number of images averaged, it does not improve significantly by averaging more than 20 images.http://europepmc.org/articles/PMC4206300?pdf=render
spellingShingle Makoto Shirasawa
Taiji Sakamoto
Hiroto Terasaki
Takehiro Yamashita
Eisuke Uchino
Shozo Sonoda
Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.
PLoS ONE
title Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.
title_full Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.
title_fullStr Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.
title_full_unstemmed Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.
title_short Objective determination of optimal number of spectral-domain optical coherence tomographic images of retina to average.
title_sort objective determination of optimal number of spectral domain optical coherence tomographic images of retina to average
url http://europepmc.org/articles/PMC4206300?pdf=render
work_keys_str_mv AT makotoshirasawa objectivedeterminationofoptimalnumberofspectraldomainopticalcoherencetomographicimagesofretinatoaverage
AT taijisakamoto objectivedeterminationofoptimalnumberofspectraldomainopticalcoherencetomographicimagesofretinatoaverage
AT hirototerasaki objectivedeterminationofoptimalnumberofspectraldomainopticalcoherencetomographicimagesofretinatoaverage
AT takehiroyamashita objectivedeterminationofoptimalnumberofspectraldomainopticalcoherencetomographicimagesofretinatoaverage
AT eisukeuchino objectivedeterminationofoptimalnumberofspectraldomainopticalcoherencetomographicimagesofretinatoaverage
AT shozosonoda objectivedeterminationofoptimalnumberofspectraldomainopticalcoherencetomographicimagesofretinatoaverage