Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
In the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and l...
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Format: | Article |
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MDPI AG
2022-10-01
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Series: | Biosensors |
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Online Access: | https://www.mdpi.com/2079-6374/12/11/937 |
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author | Meizhen Zhang Qian Yu Jiaqi Guo Bo Wu Xianming Kong |
author_facet | Meizhen Zhang Qian Yu Jiaqi Guo Bo Wu Xianming Kong |
author_sort | Meizhen Zhang |
collection | DOAJ |
description | In the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and low cost. Therefore, the TLC-SERS has great potential for detecting analytes in mixtures without sample pretreatment. The review demonstrates TLC-SERS applications in diverse analytical relevant topics such as environmental pollutants, illegal additives, pesticide residues, toxic ingredients, biological molecules, and chemical substances. Important properties such as stationary phase, separation efficiency, and sensitivity are discussed. In addition, future perspectives for improving the efficiency of TLC-SERS in real sample detecting are outlined. |
first_indexed | 2024-03-09T19:14:15Z |
format | Article |
id | doaj.art-7e32bcad5b004e118758a9a23bdcea03 |
institution | Directory Open Access Journal |
issn | 2079-6374 |
language | English |
last_indexed | 2024-03-09T19:14:15Z |
publishDate | 2022-10-01 |
publisher | MDPI AG |
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series | Biosensors |
spelling | doaj.art-7e32bcad5b004e118758a9a23bdcea032023-11-24T03:54:41ZengMDPI AGBiosensors2079-63742022-10-01121193710.3390/bios12110937Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture SamplesMeizhen Zhang0Qian Yu1Jiaqi Guo2Bo Wu3Xianming Kong4School of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, ChinaSchool of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, ChinaJiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources and Joint International Research Lab of Lignocellulosic Functional Materials, Nanjing Forestry University, Nanjing 210037, ChinaSchool of Electrical Engineering and Computer Science, Oregon State University, Corvallis, OR 97331, USASchool of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, ChinaIn the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and low cost. Therefore, the TLC-SERS has great potential for detecting analytes in mixtures without sample pretreatment. The review demonstrates TLC-SERS applications in diverse analytical relevant topics such as environmental pollutants, illegal additives, pesticide residues, toxic ingredients, biological molecules, and chemical substances. Important properties such as stationary phase, separation efficiency, and sensitivity are discussed. In addition, future perspectives for improving the efficiency of TLC-SERS in real sample detecting are outlined.https://www.mdpi.com/2079-6374/12/11/937TLC-SERSseparationdetectionreal sample |
spellingShingle | Meizhen Zhang Qian Yu Jiaqi Guo Bo Wu Xianming Kong Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples Biosensors TLC-SERS separation detection real sample |
title | Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples |
title_full | Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples |
title_fullStr | Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples |
title_full_unstemmed | Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples |
title_short | Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples |
title_sort | review of thin layer chromatography tandem with surface enhanced raman spectroscopy for detection of analytes in mixture samples |
topic | TLC-SERS separation detection real sample |
url | https://www.mdpi.com/2079-6374/12/11/937 |
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