Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples

In the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and l...

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Main Authors: Meizhen Zhang, Qian Yu, Jiaqi Guo, Bo Wu, Xianming Kong
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/12/11/937
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author Meizhen Zhang
Qian Yu
Jiaqi Guo
Bo Wu
Xianming Kong
author_facet Meizhen Zhang
Qian Yu
Jiaqi Guo
Bo Wu
Xianming Kong
author_sort Meizhen Zhang
collection DOAJ
description In the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and low cost. Therefore, the TLC-SERS has great potential for detecting analytes in mixtures without sample pretreatment. The review demonstrates TLC-SERS applications in diverse analytical relevant topics such as environmental pollutants, illegal additives, pesticide residues, toxic ingredients, biological molecules, and chemical substances. Important properties such as stationary phase, separation efficiency, and sensitivity are discussed. In addition, future perspectives for improving the efficiency of TLC-SERS in real sample detecting are outlined.
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spelling doaj.art-7e32bcad5b004e118758a9a23bdcea032023-11-24T03:54:41ZengMDPI AGBiosensors2079-63742022-10-01121193710.3390/bios12110937Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture SamplesMeizhen Zhang0Qian Yu1Jiaqi Guo2Bo Wu3Xianming Kong4School of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, ChinaSchool of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, ChinaJiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources and Joint International Research Lab of Lignocellulosic Functional Materials, Nanjing Forestry University, Nanjing 210037, ChinaSchool of Electrical Engineering and Computer Science, Oregon State University, Corvallis, OR 97331, USASchool of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, ChinaIn the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and low cost. Therefore, the TLC-SERS has great potential for detecting analytes in mixtures without sample pretreatment. The review demonstrates TLC-SERS applications in diverse analytical relevant topics such as environmental pollutants, illegal additives, pesticide residues, toxic ingredients, biological molecules, and chemical substances. Important properties such as stationary phase, separation efficiency, and sensitivity are discussed. In addition, future perspectives for improving the efficiency of TLC-SERS in real sample detecting are outlined.https://www.mdpi.com/2079-6374/12/11/937TLC-SERSseparationdetectionreal sample
spellingShingle Meizhen Zhang
Qian Yu
Jiaqi Guo
Bo Wu
Xianming Kong
Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
Biosensors
TLC-SERS
separation
detection
real sample
title Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
title_full Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
title_fullStr Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
title_full_unstemmed Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
title_short Review of Thin-Layer Chromatography Tandem with Surface-Enhanced Raman Spectroscopy for Detection of Analytes in Mixture Samples
title_sort review of thin layer chromatography tandem with surface enhanced raman spectroscopy for detection of analytes in mixture samples
topic TLC-SERS
separation
detection
real sample
url https://www.mdpi.com/2079-6374/12/11/937
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