Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report
A 34-year-old nulliparous gravid female presented with acute bilateral pyelonephritis at 29 + 5 weeks gestation. The patient was relatively well until two weeks ago when a slight increase in amniotic fluid was noted. Further investigation revealed myoglobinuria and significantly elevated levels of c...
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MDPI AG
2023-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/5/824 |
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| author | Hyun Mi Kim Heejeong Kim Hyun-Hwa Cha Haemin Kim Hyo-Shin Kim Mi Ju Kim |
| author_facet | Hyun Mi Kim Heejeong Kim Hyun-Hwa Cha Haemin Kim Hyo-Shin Kim Mi Ju Kim |
| author_sort | Hyun Mi Kim |
| collection | DOAJ |
| description | A 34-year-old nulliparous gravid female presented with acute bilateral pyelonephritis at 29 + 5 weeks gestation. The patient was relatively well until two weeks ago when a slight increase in amniotic fluid was noted. Further investigation revealed myoglobinuria and significantly elevated levels of creatine phosphokinase. The patient was subsequently diagnosed with rhabdomyolysis. Twelve hours after admission, the patient noted reduced fetal movements. A non-stress test revealed fetal bradycardia and non-reassuring variability in fetal heart rate. An emergency cesarean section was performed, and a “floppy” female child was delivered. Genetic testing revealed congenital myotonic dystrophy, and the mother was also diagnosed with myotonic dystrophy. Rhabdomyolysis has a very low incidence in pregnancy. Herein, we report a rare case of myotonic dystrophy with rhabdomyolysis in a gravid female with no history of myotonic dystrophy. Acute pyelonephritis is a causative agent of rhabdomyolysis that results in preterm birth. |
| first_indexed | 2024-03-11T03:31:22Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T03:31:22Z |
| publishDate | 2023-04-01 |
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| series | Medicina |
| spelling | doaj.art-7e33793439684fa4a380631fea9ebe692023-11-18T02:20:42ZengMDPI AGMedicina1010-660X1648-91442023-04-0159582410.3390/medicina59050824Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case ReportHyun Mi Kim0Heejeong Kim1Hyun-Hwa Cha2Haemin Kim3Hyo-Shin Kim4Mi Ju Kim5Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu 41944, Republic of KoreaDepartment of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu 41944, Republic of KoreaDepartment of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu 41944, Republic of KoreaDepartment of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu 41404, Republic of KoreaDepartment of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu 41404, Republic of KoreaDepartment of Obstetrics and Gynecology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu 41944, Republic of KoreaA 34-year-old nulliparous gravid female presented with acute bilateral pyelonephritis at 29 + 5 weeks gestation. The patient was relatively well until two weeks ago when a slight increase in amniotic fluid was noted. Further investigation revealed myoglobinuria and significantly elevated levels of creatine phosphokinase. The patient was subsequently diagnosed with rhabdomyolysis. Twelve hours after admission, the patient noted reduced fetal movements. A non-stress test revealed fetal bradycardia and non-reassuring variability in fetal heart rate. An emergency cesarean section was performed, and a “floppy” female child was delivered. Genetic testing revealed congenital myotonic dystrophy, and the mother was also diagnosed with myotonic dystrophy. Rhabdomyolysis has a very low incidence in pregnancy. Herein, we report a rare case of myotonic dystrophy with rhabdomyolysis in a gravid female with no history of myotonic dystrophy. Acute pyelonephritis is a causative agent of rhabdomyolysis that results in preterm birth.https://www.mdpi.com/1648-9144/59/5/824acute pyelonephritismyotonic dystrophypolyhydramniospregnancyrhabdomyolysis |
| spellingShingle | Hyun Mi Kim Heejeong Kim Hyun-Hwa Cha Haemin Kim Hyo-Shin Kim Mi Ju Kim Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report Medicina acute pyelonephritis myotonic dystrophy polyhydramnios pregnancy rhabdomyolysis |
| title | Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report |
| title_full | Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report |
| title_fullStr | Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report |
| title_full_unstemmed | Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report |
| title_short | Infection-Induced Rhabdomyolysis in a Pregnant Woman with Undiagnosed Myotonic Dystrophy: A Case Report |
| title_sort | infection induced rhabdomyolysis in a pregnant woman with undiagnosed myotonic dystrophy a case report |
| topic | acute pyelonephritis myotonic dystrophy polyhydramnios pregnancy rhabdomyolysis |
| url | https://www.mdpi.com/1648-9144/59/5/824 |
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