Novel MLPA procedure using self-designed probes allows comprehensive analysis for CNVs of the genes involved in Hirschsprung disease

Novel MLPA procedure using self-designed probes allows comprehensive analysis for CNVs of the genes involved in Hirschsprung disease

<p>Abstract</p> <p>Background</p> <p>Hirschsprung disease is characterized by the absence of intramural ganglion cells in the enteric plexuses, due to a fail during enteric nervous system formation. Hirschsprung has a complex genetic aetiology and mutations in several g...

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Bibliographic Details
Main Authors:	Antiñolo Guillermo, Fernández Raquel M, Núñez-Torres Rocio, Sánchez-Mejías Avencia, Borrego Salud
Format:	Article
Language:	English
Published:	BMC 2010-05-01
Series:	BMC Medical Genetics
Online Access:	http://www.biomedcentral.com/1471-2350/11/71

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