Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption
Background: Diabetes mellitus is a common disease in most parts of the world, the metabolic abnormalities of diabetes potentially affect bone metabolism, structure, mineral density, and bone resorption, as part of physiological bone turnover. Aim: This study aimed to estimate urinary total deoxypyr...
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| Format: | Article |
| Language: | English |
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University of Thi-Qar
2019-04-01
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| Series: | مجلة علوم ذي قار |
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| Online Access: | https://www.jsci.utq.edu.iq/index.php/main/article/view/76 |
| _version_ | 1827738327031218176 |
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| author | Zainab Ali Kadhem |
| author_facet | Zainab Ali Kadhem |
| author_sort | Zainab Ali Kadhem |
| collection | DOAJ |
| description | Background: Diabetes mellitus is a common disease in most parts of the world, the metabolic abnormalities of diabetes potentially affect bone metabolism, structure, mineral density, and bone resorption, as part of physiological bone turnover.
Aim: This study aimed to estimate urinary total deoxypyridinoline as a biomarker of mature bone collagen degradation and bone resorption in type I diabetes mellitus patients and evaluate its relationship with fasting blood sugar, serum bone minerals profile and the duration of disease and also to investigate the degree of severity of bone resorption and the probability of fracture risk.
Patients and methods:165patients with type I diabetes mellitus from Diabetes mellitus and Endocrine Disease Centre at AL -Nasiriyah city in Thi-Qar province, Iraq were studied.100 (60.6%) were female and 65(39.4%) were male, age was between(25-65) year, mean44.27 |
| first_indexed | 2024-03-11T02:42:48Z |
| format | Article |
| id | doaj.art-7e38967a4e7649aea309cf10d920799d |
| institution | Directory Open Access Journal |
| issn | 1991-8690 2709-0256 |
| language | English |
| last_indexed | 2024-03-11T02:42:48Z |
| publishDate | 2019-04-01 |
| publisher | University of Thi-Qar |
| record_format | Article |
| series | مجلة علوم ذي قار |
| spelling | doaj.art-7e38967a4e7649aea309cf10d920799d2023-11-18T09:30:16ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562019-04-0164Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone ResorptionZainab Ali Kadhem0Department of Clinical Chemistry/ College of Medicine/Thi- Qar UniversityBackground: Diabetes mellitus is a common disease in most parts of the world, the metabolic abnormalities of diabetes potentially affect bone metabolism, structure, mineral density, and bone resorption, as part of physiological bone turnover. Aim: This study aimed to estimate urinary total deoxypyridinoline as a biomarker of mature bone collagen degradation and bone resorption in type I diabetes mellitus patients and evaluate its relationship with fasting blood sugar, serum bone minerals profile and the duration of disease and also to investigate the degree of severity of bone resorption and the probability of fracture risk. Patients and methods:165patients with type I diabetes mellitus from Diabetes mellitus and Endocrine Disease Centre at AL -Nasiriyah city in Thi-Qar province, Iraq were studied.100 (60.6%) were female and 65(39.4%) were male, age was between(25-65) year, mean44.27https://www.jsci.utq.edu.iq/index.php/main/article/view/76Urinary total deoxypyridinolinebone minerals profilebone resorptiontype I diabetes mellitus |
| spellingShingle | Zainab Ali Kadhem Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption مجلة علوم ذي قار Urinary total deoxypyridinoline bone minerals profile bone resorption type I diabetes mellitus |
| title | Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption |
| title_full | Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption |
| title_fullStr | Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption |
| title_full_unstemmed | Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption |
| title_short | Evaluation of Bone Resorption in Type I diabetes Mellitus Patients by Measuring Urinary Total Deoxypyridinoline ( U. DPD) as a Biomarker of Bone Resorption |
| title_sort | evaluation of bone resorption in type i diabetes mellitus patients by measuring urinary total deoxypyridinoline u dpd as a biomarker of bone resorption |
| topic | Urinary total deoxypyridinoline bone minerals profile bone resorption type I diabetes mellitus |
| url | https://www.jsci.utq.edu.iq/index.php/main/article/view/76 |
| work_keys_str_mv | AT zainabalikadhem evaluationofboneresorptionintypeidiabetesmellituspatientsbymeasuringurinarytotaldeoxypyridinolineudpdasabiomarkerofboneresorption |