Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII.

Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII.

TRAnsport Protein Particle complexes (TRAPPs) are ubiquitous regulators of membrane traffic mediating nucleotide exchange on the Golgi regulatory GTPases RAB1 and RAB11. In S. cerevisiae and metazoans TRAPPs consist of two large oligomeric complexes: RAB11-activating TRAPPII and RAB1-activating TRAP...

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Bibliographic Details
Main Authors: Mario Pinar, Ernesto Arias-Palomo, Vivian de Los Ríos, Herbert N Arst, Miguel A Peñalva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008557

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