Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine
Acenocoumarol is the global standard of anticoagulant therapy, but often treatment with acenocoumarol accompanied by adverse drug reactions. Model of personalized medicine, actively developing now, can reduce the number of side effects during therapy of Acenocoumarol, mainly due to individual geneti...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Peoples’ Friendship University of Russia (RUDN University)
2009-12-01
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| Series: | RUDN Journal of Medicine |
| Subjects: | |
| Online Access: | http://journals.rudn.ru/medicine/article/view/2526 |
| _version_ | 1819123403883282432 |
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| author | I V Kukes V N Shan |
| author_facet | I V Kukes V N Shan |
| author_sort | I V Kukes |
| collection | DOAJ |
| description | Acenocoumarol is the global standard of anticoagulant therapy, but often treatment with acenocoumarol accompanied by adverse drug reactions. Model of personalized medicine, actively developing now, can reduce the number of side effects during therapy of Acenocoumarol, mainly due to individual genetic characteristics (polymorphisms of genes CYP2C9 and VKORC1). This will help to reduce side effects of therapy and reduce treatment costs. |
| first_indexed | 2024-12-22T07:07:48Z |
| format | Article |
| id | doaj.art-7e3a81a35b92450da9d03f00ac878803 |
| institution | Directory Open Access Journal |
| issn | 2313-0245 2313-0261 |
| language | English |
| last_indexed | 2024-12-22T07:07:48Z |
| publishDate | 2009-12-01 |
| publisher | Peoples’ Friendship University of Russia (RUDN University) |
| record_format | Article |
| series | RUDN Journal of Medicine |
| spelling | doaj.art-7e3a81a35b92450da9d03f00ac8788032022-12-21T18:34:37ZengPeoples’ Friendship University of Russia (RUDN University)RUDN Journal of Medicine2313-02452313-02612009-12-01044214232526Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicineI V Kukes0V N Shan1Московская медицинская академия имени И.М. СеченоваМосковский государственный университет имени М.В. ЛомоносоваAcenocoumarol is the global standard of anticoagulant therapy, but often treatment with acenocoumarol accompanied by adverse drug reactions. Model of personalized medicine, actively developing now, can reduce the number of side effects during therapy of Acenocoumarol, mainly due to individual genetic characteristics (polymorphisms of genes CYP2C9 and VKORC1). This will help to reduce side effects of therapy and reduce treatment costs.http://journals.rudn.ru/medicine/article/view/2526здравоохранениесмертностькровотечения |
| spellingShingle | I V Kukes V N Shan Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine RUDN Journal of Medicine здравоохранение смертность кровотечения |
| title | Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine |
| title_full | Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine |
| title_fullStr | Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine |
| title_full_unstemmed | Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine |
| title_short | Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine |
| title_sort | efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation with using models of personalized medicine |
| topic | здравоохранение смертность кровотечения |
| url | http://journals.rudn.ru/medicine/article/view/2526 |
| work_keys_str_mv | AT ivkukes efficiencyoftreatmentbyacenocoumarolinpatientswithpermanentformofatrialfibrillationwithusingmodelsofpersonalizedmedicine AT vnshan efficiencyoftreatmentbyacenocoumarolinpatientswithpermanentformofatrialfibrillationwithusingmodelsofpersonalizedmedicine |