Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine

The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute...

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Main Authors: Morgan Lombardo, Amanda DiPiazza, Kelly Rippey, Naomi Lubarr, Elana Clar, Hooman Azmi
Format: Article
Language:English
Published: Korean Movement Disorder Society 2020-05-01
Series:Journal of Movement Disorders
Subjects:
Online Access:http://www.e-jmd.org/upload/jmd-20005.pdf
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author Morgan Lombardo
Amanda DiPiazza
Kelly Rippey
Naomi Lubarr
Elana Clar
Hooman Azmi
author_facet Morgan Lombardo
Amanda DiPiazza
Kelly Rippey
Naomi Lubarr
Elana Clar
Hooman Azmi
author_sort Morgan Lombardo
collection DOAJ
description The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.
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spelling doaj.art-7e3e95d324894f66a2a77504c539fff32023-08-02T07:55:39ZengKorean Movement Disorder SocietyJournal of Movement Disorders2005-940X2093-49392020-05-0113215916210.14802/jmd.20005289Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of DexmedetomidineMorgan Lombardo0Amanda DiPiazza1Kelly Rippey2Naomi Lubarr3Elana Clar4Hooman Azmi5 Department of Neurosurgery, Hackensack University Medical Center, Hackensack, NJ, USA Department of Neurosurgery, Hackensack University Medical Center, Hackensack, NJ, USA Division of Trauma and Critical Care, Department of Surgery, Hackensack University Medical Center, Hackensack, NJ, USA Department of Neurology, Hackensack University Medical Center, Hackensack, NJ, USA North Jersey Brain and Spine Center, Hackensack, NJ, USA Department of Neurosurgery, Hackensack University Medical Center, Hackensack, NJ, USAThe treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.http://www.e-jmd.org/upload/jmd-20005.pdfdeliriumdexmedetomidineparkinson’s diseasetreatment
spellingShingle Morgan Lombardo
Amanda DiPiazza
Kelly Rippey
Naomi Lubarr
Elana Clar
Hooman Azmi
Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
Journal of Movement Disorders
delirium
dexmedetomidine
parkinson’s disease
treatment
title Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_full Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_fullStr Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_full_unstemmed Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_short Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_sort treatment of acute delirium in a patient with parkinson s disease by transfer to the intensive care unit and administration of dexmedetomidine
topic delirium
dexmedetomidine
parkinson’s disease
treatment
url http://www.e-jmd.org/upload/jmd-20005.pdf
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