Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae)
Abstract Mutisia L. f. (Mutisiinae, Mutisieae, Mutisioideae, Asteraceae) is a South American genus that contains several medicinal species. Mutisia acuminata Ruiz & Pav. and M. orbignyana Wedd. are known sources of the 12-dihydroxy-5-methylcoumestan and 5-methylcoumarin-4-glucoside respectively....
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| Format: | Article |
| Language: | English |
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Instituto de Tecnologia do Paraná (Tecpar)
2023-09-01
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| Series: | Brazilian Archives of Biology and Technology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000400801&lng=en&tlng=en |
| _version_ | 1797681801629532160 |
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| author | Dina Pillco Paulo Gari Vidal Ccana-Ccapatinta Carlos Alberto Serrano Flores |
| author_facet | Dina Pillco Paulo Gari Vidal Ccana-Ccapatinta Carlos Alberto Serrano Flores |
| author_sort | Dina Pillco Paulo |
| collection | DOAJ |
| description | Abstract Mutisia L. f. (Mutisiinae, Mutisieae, Mutisioideae, Asteraceae) is a South American genus that contains several medicinal species. Mutisia acuminata Ruiz & Pav. and M. orbignyana Wedd. are known sources of the 12-dihydroxy-5-methylcoumestan and 5-methylcoumarin-4-glucoside respectively. The 12-dihydroxy-5-methylcoumestan exhibited notable antihepatotoxic activity in a previous study. In the present work, 5-methylcoumarin-4-glucoside and 12-dihydroxy-5-methylcoumestan were isolated from a Peruvian collection of M. orbignyana. Additionally, the relative concentrations of those two isolated compounds in six Peruvian species of Mutisia (M. acuminata, M. cochabambensis Hieron., M. lanata Ruiz & Pav., M. orbignyana, M. venusta S.F. Blake and M. wurdackii Cabrera) were determined by an HPLC method. The highest concentrations of both constituents were observed in the sample of M. orbignyana. |
| first_indexed | 2024-03-11T23:50:17Z |
| format | Article |
| id | doaj.art-7e3ff8405f944c63a6db948f68abc199 |
| institution | Directory Open Access Journal |
| issn | 1678-4324 |
| language | English |
| last_indexed | 2024-03-11T23:50:17Z |
| publishDate | 2023-09-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-7e3ff8405f944c63a6db948f68abc1992023-09-19T07:43:34ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1678-43242023-09-0166spe10.1590/1678-4324-ssbfar-2023220978Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae)Dina Pillco Paulohttps://orcid.org/0000-0002-5223-0532Gari Vidal Ccana-Ccapatintahttps://orcid.org/0000-0002-1863-0524Carlos Alberto Serrano Floreshttps://orcid.org/0000-0003-0462-709XAbstract Mutisia L. f. (Mutisiinae, Mutisieae, Mutisioideae, Asteraceae) is a South American genus that contains several medicinal species. Mutisia acuminata Ruiz & Pav. and M. orbignyana Wedd. are known sources of the 12-dihydroxy-5-methylcoumestan and 5-methylcoumarin-4-glucoside respectively. The 12-dihydroxy-5-methylcoumestan exhibited notable antihepatotoxic activity in a previous study. In the present work, 5-methylcoumarin-4-glucoside and 12-dihydroxy-5-methylcoumestan were isolated from a Peruvian collection of M. orbignyana. Additionally, the relative concentrations of those two isolated compounds in six Peruvian species of Mutisia (M. acuminata, M. cochabambensis Hieron., M. lanata Ruiz & Pav., M. orbignyana, M. venusta S.F. Blake and M. wurdackii Cabrera) were determined by an HPLC method. The highest concentrations of both constituents were observed in the sample of M. orbignyana.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000400801&lng=en&tlng=enMutisiaAsteraceae5-methylcoumarincoumestan |
| spellingShingle | Dina Pillco Paulo Gari Vidal Ccana-Ccapatinta Carlos Alberto Serrano Flores Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae) Brazilian Archives of Biology and Technology Mutisia Asteraceae 5-methylcoumarin coumestan |
| title | Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae) |
| title_full | Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae) |
| title_fullStr | Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae) |
| title_full_unstemmed | Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae) |
| title_short | Quantification of 5-methylcoumarin-4-glucoside and 11,12-dihydroxy-5-methylcoumestan in Six Peruvian Species of the Genus Mutisia (Asteraceae) |
| title_sort | quantification of 5 methylcoumarin 4 glucoside and 11 12 dihydroxy 5 methylcoumestan in six peruvian species of the genus mutisia asteraceae |
| topic | Mutisia Asteraceae 5-methylcoumarin coumestan |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000400801&lng=en&tlng=en |
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