ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN
One of the great challenges in the treatment of infectious diseases is the resistance of pathogenic bacteria against antibiotics, and antibiotic resistance to Shigella is broadly observed in different parts of the world. The object of this study was to determine Shigella antibiotic resistance patter...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2008-10-01
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| Series: | Acta Medica Iranica |
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| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3510 |
| _version_ | 1818644228167696384 |
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| author | M Qureishi A Borji M Bokaeian M Roudbari S Shahraki A Niazi M Zangiabadi |
| author_facet | M Qureishi A Borji M Bokaeian M Roudbari S Shahraki A Niazi M Zangiabadi |
| author_sort | M Qureishi |
| collection | DOAJ |
| description | One of the great challenges in the treatment of infectious diseases is the resistance of pathogenic bacteria against antibiotics, and antibiotic resistance to Shigella is broadly observed in different parts of the world. The object of this study was to determine Shigella antibiotic resistance pattern against the antibiotics such as ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, chloramphenicol, nalidixic acid, ciprofloxacin and ceftriaxone. In this cross-sectional study, a total of 147 Shigella strains were collected from the diarrheic patients referring to different medical centers of Zahedan. Specific antisera were used for serotyping of isolated Shigella and their antibiotic resistance patterns were determined by standard Kirby-Bauer method. Of the 147 studied Shigella strains, 102 (69.3%) belonged to S. flexneri, 32 (21.7 %) to S. dysenteriae, 11 (7.4%) to S. boydii, and 2 (1.36%) to S. sonnei species. The isolated strains showed resistance to ampicillin (99.3%), trimethoprim-sulfamethoxazole (52%) and nalidixic acid (1.3%), but there was no resistance against ciprofloxacin and ceftriaxone. According to the findings, it is suggested that antibiotics should not be used without laboratory testing (antibiogram). |
| first_indexed | 2024-12-17T00:11:31Z |
| format | Article |
| id | doaj.art-7e40f0f563684fe388db150245cc126c |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-17T00:11:31Z |
| publishDate | 2008-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-7e40f0f563684fe388db150245cc126c2022-12-21T22:10:49ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942008-10-01465ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDANM Qureishi0A Borji1M Bokaeian2M Roudbari3S Shahraki4A Niazi5M Zangiabadi61) Department of Microbiology, School of Medicine, Zahedan University of medical Sciences, Zahedan, 1) Department of Microbiology, School of Medicine, Zahedan University of medical Sciences, Zahedan, 1) Department of Microbiology, School of Medicine, Zahedan University of medical Sciences, Zahedan, 2) Department of Statistics and Mathematics, Management and Medical Information School, Iran Univers1) Department of Microbiology, School of Medicine, Zahedan University of medical Sciences, Zahedan, 3) Department of Pathology, School of Medicine, Zahedan University of medical Sciences, Zahedan, Ira1) Department of Microbiology, School of Medicine, Zahedan University of medical Sciences, Zahedan, One of the great challenges in the treatment of infectious diseases is the resistance of pathogenic bacteria against antibiotics, and antibiotic resistance to Shigella is broadly observed in different parts of the world. The object of this study was to determine Shigella antibiotic resistance pattern against the antibiotics such as ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, chloramphenicol, nalidixic acid, ciprofloxacin and ceftriaxone. In this cross-sectional study, a total of 147 Shigella strains were collected from the diarrheic patients referring to different medical centers of Zahedan. Specific antisera were used for serotyping of isolated Shigella and their antibiotic resistance patterns were determined by standard Kirby-Bauer method. Of the 147 studied Shigella strains, 102 (69.3%) belonged to S. flexneri, 32 (21.7 %) to S. dysenteriae, 11 (7.4%) to S. boydii, and 2 (1.36%) to S. sonnei species. The isolated strains showed resistance to ampicillin (99.3%), trimethoprim-sulfamethoxazole (52%) and nalidixic acid (1.3%), but there was no resistance against ciprofloxacin and ceftriaxone. According to the findings, it is suggested that antibiotics should not be used without laboratory testing (antibiogram).https://acta.tums.ac.ir/index.php/acta/article/view/3510Shigellaantimicrobial resistanceantibioticdiarrhea |
| spellingShingle | M Qureishi A Borji M Bokaeian M Roudbari S Shahraki A Niazi M Zangiabadi ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN Acta Medica Iranica Shigella antimicrobial resistance antibiotic diarrhea |
| title | ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN |
| title_full | ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN |
| title_fullStr | ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN |
| title_full_unstemmed | ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN |
| title_short | ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN |
| title_sort | antimicrobial resistance of shigella spp isolated from diarrheal patients in zahedan |
| topic | Shigella antimicrobial resistance antibiotic diarrhea |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3510 |
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