The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration
Some studies suggest that eating more than one egg daily may increase risk of death from cardiovascular disease. The objective of this study was to determine the effects of consuming eggs on various serum markers associated with cardiovascular disease (CVD). Forty-five independently living adults di...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-03-01
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| Series: | Journal of Nutrition & Intermediary Metabolism |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352385918300070 |
| _version_ | 1811205232235905024 |
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| author | Hassan Aljohi Mindy Dopler-Nelson Manuel Cifuentes Thomas A. Wilson |
| author_facet | Hassan Aljohi Mindy Dopler-Nelson Manuel Cifuentes Thomas A. Wilson |
| author_sort | Hassan Aljohi |
| collection | DOAJ |
| description | Some studies suggest that eating more than one egg daily may increase risk of death from cardiovascular disease. The objective of this study was to determine the effects of consuming eggs on various serum markers associated with cardiovascular disease (CVD). Forty-five independently living adults diagnosed with early macular degeneration, but healthy otherwise were recruited into the study. Subjects were placed into the Intervention (n = 27) or Control group (n = 18) based on whether or not they would consume eggs. The Intervention group consumed 12 eggs per week while the Control group refrained from consuming any whole egg products for 1 year. Serum concentrations of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), glucose, apolipoprotein (apo) A-1 and apo B, lipoprotein (Lp)a and high-sensitive C reactive protein (hsCRP) were measured at baseline, 6, and 12 months. Serum low-density lipoprotein cholesterol (LDL-C) concentration was calculated via the Friedewald equation. Serum TC, TG, HDL-C, LDL-C, apo A-1, apo B, Lpa and hsCRP concentrations did not change at any time in both the Intervention and Control groups compared to baseline nor were there any differences between the two treatment. Serum glucose concentrations did increase significantly in the Intervention group at 6 months compared to baseline (23%, P < 0.05) but decreased back to baseline concentrations at 12 months. This study suggests that the consumption of 12 eggs per week for 1 year does not significantly alter fasting serum lipids, lipoprotein cholesterol, or other biomarkers of CVD in older adults diagnosed with early macular degeneration. Keywords: Apolipoprotein A-1, Apolipoprotein B, C-reactive protein (CRP), Cardiovascular disease (CVD), HDL cholesterol, LDL cholesterol |
| first_indexed | 2024-04-12T03:27:17Z |
| format | Article |
| id | doaj.art-7e47af5f6c6b431d8c6cd5725f951916 |
| institution | Directory Open Access Journal |
| issn | 2352-3859 |
| language | English |
| last_indexed | 2024-04-12T03:27:17Z |
| publishDate | 2019-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Nutrition & Intermediary Metabolism |
| spelling | doaj.art-7e47af5f6c6b431d8c6cd5725f9519162022-12-22T03:49:38ZengElsevierJournal of Nutrition & Intermediary Metabolism2352-38592019-03-01153541The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degenerationHassan Aljohi0Mindy Dopler-Nelson1Manuel Cifuentes2Thomas A. Wilson3Biomedical Engineering and Biotechnology Program, University of Massachusetts Lowell, Lowell, MA, USABiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell, Lowell, MA, USADepartment of Public Health, Regis College, Weston, MA, USABiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell, Lowell, MA, USA; Department of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA, USA; Corresponding author. Department of Biomedical and Nutritional Sciences, 3 Solomont Way, Suite 4, University of Massachusetts Lowell; Lowell, MA, 01854, United States.Some studies suggest that eating more than one egg daily may increase risk of death from cardiovascular disease. The objective of this study was to determine the effects of consuming eggs on various serum markers associated with cardiovascular disease (CVD). Forty-five independently living adults diagnosed with early macular degeneration, but healthy otherwise were recruited into the study. Subjects were placed into the Intervention (n = 27) or Control group (n = 18) based on whether or not they would consume eggs. The Intervention group consumed 12 eggs per week while the Control group refrained from consuming any whole egg products for 1 year. Serum concentrations of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), glucose, apolipoprotein (apo) A-1 and apo B, lipoprotein (Lp)a and high-sensitive C reactive protein (hsCRP) were measured at baseline, 6, and 12 months. Serum low-density lipoprotein cholesterol (LDL-C) concentration was calculated via the Friedewald equation. Serum TC, TG, HDL-C, LDL-C, apo A-1, apo B, Lpa and hsCRP concentrations did not change at any time in both the Intervention and Control groups compared to baseline nor were there any differences between the two treatment. Serum glucose concentrations did increase significantly in the Intervention group at 6 months compared to baseline (23%, P < 0.05) but decreased back to baseline concentrations at 12 months. This study suggests that the consumption of 12 eggs per week for 1 year does not significantly alter fasting serum lipids, lipoprotein cholesterol, or other biomarkers of CVD in older adults diagnosed with early macular degeneration. Keywords: Apolipoprotein A-1, Apolipoprotein B, C-reactive protein (CRP), Cardiovascular disease (CVD), HDL cholesterol, LDL cholesterolhttp://www.sciencedirect.com/science/article/pii/S2352385918300070 |
| spellingShingle | Hassan Aljohi Mindy Dopler-Nelson Manuel Cifuentes Thomas A. Wilson The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration Journal of Nutrition & Intermediary Metabolism |
| title | The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration |
| title_full | The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration |
| title_fullStr | The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration |
| title_full_unstemmed | The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration |
| title_short | The consumption of 12 Eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration |
| title_sort | consumption of 12 eggs per week for 1 year does not alter fasting serum markers of cardiovascular disease in older adults with early macular degeneration |
| url | http://www.sciencedirect.com/science/article/pii/S2352385918300070 |
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