When the single matters more than the group (II): addressing the problem of high false positive rates in single case Voxel Based Morphometry using non-parametric statistics

When the single matters more than the group (II): addressing the problem of high false positive rates in single case Voxel Based Morphometry using non-parametric statistics

In recent years, an increasing number of studies have used Voxel Based Morphometry (VBM) to compare a single patient with a psychiatric or neurological condition of interest against a group of healthy controls. However, the validity of this approach critically relies on the assumption that the singl...

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Bibliographic Details
Main Authors: Cristina eScarpazza, Thomas E. Nichols, Donato eSeramondi, Camille eMaumet, Giuseppe eSartori, Andrea eMechelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Neuroscience
Subjects:
Magnetic Resonance Imaging
Neuroimaging
Voxel Based Morphometry
Non-parametric statistics
single case study
False positives
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00006/full

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