Histopathological effects of Doxorubicin on pancreas in male Albino rats
The aim of this study was to investigate the histopathological side effects of doxorubicin on pancreas tissue in male albino rats Rattus norvegicus. This study were used 55 adult rats (2.5-3.5) month of age. The rats divided into two groups, the first group include (35) rats. The second group were (...
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| Format: | Article |
| Language: | Arabic |
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University of Mosul, College of Veterinary Medicine
2015-12-01
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| Series: | Iraqi Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | https://vetmedmosul.com/article_116852_67a59e4ea88c559d3fe1cc5dc815e607.pdf |
| _version_ | 1819001168356966400 |
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| author | I.A. Ali H.J. Jumaa H.Kh. Ismael |
| author_facet | I.A. Ali H.J. Jumaa H.Kh. Ismael |
| author_sort | I.A. Ali |
| collection | DOAJ |
| description | The aim of this study was to investigate the histopathological side effects of doxorubicin on pancreas tissue in male albino
rats Rattus norvegicus. This study were used 55 adult rats (2.5-3.5) month of age. The rats divided into two groups, the first
group include (35) rats. The second group were (20) rats. Microscopial examination of pancreas lesion demonstrated oedema
around the acini, swelling of the epithelial cells of acini, occurance of cystic fibrosis (mucoviscidosis) at the concentration of
(4,5) mg/kg of body weight ,occurrence of small islets that form of few cells and exocrine-endocrine transformation. There
were thickness in the walls of blood vessels, thrombus, congestion of blood vessels, we conclude, that doxorubicin had
histopathological effect on pancreas in sub-acute doses more than chronic doses. |
| first_indexed | 2024-12-20T22:44:55Z |
| format | Article |
| id | doaj.art-7e4c89f11449480dac038a20ac9be0e9 |
| institution | Directory Open Access Journal |
| issn | 1607-3894 2071-1255 |
| language | Arabic |
| last_indexed | 2024-12-20T22:44:55Z |
| publishDate | 2015-12-01 |
| publisher | University of Mosul, College of Veterinary Medicine |
| record_format | Article |
| series | Iraqi Journal of Veterinary Sciences |
| spelling | doaj.art-7e4c89f11449480dac038a20ac9be0e92022-12-21T19:24:24ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552015-12-01291232810.33899/ijvs.2015.116852116852Histopathological effects of Doxorubicin on pancreas in male Albino ratsI.A. AliH.J. JumaaH.Kh. IsmaelThe aim of this study was to investigate the histopathological side effects of doxorubicin on pancreas tissue in male albino rats Rattus norvegicus. This study were used 55 adult rats (2.5-3.5) month of age. The rats divided into two groups, the first group include (35) rats. The second group were (20) rats. Microscopial examination of pancreas lesion demonstrated oedema around the acini, swelling of the epithelial cells of acini, occurance of cystic fibrosis (mucoviscidosis) at the concentration of (4,5) mg/kg of body weight ,occurrence of small islets that form of few cells and exocrine-endocrine transformation. There were thickness in the walls of blood vessels, thrombus, congestion of blood vessels, we conclude, that doxorubicin had histopathological effect on pancreas in sub-acute doses more than chronic doses.https://vetmedmosul.com/article_116852_67a59e4ea88c559d3fe1cc5dc815e607.pdfhistopathological effectsdoxorubicinpancreasmale albino rats |
| spellingShingle | I.A. Ali H.J. Jumaa H.Kh. Ismael Histopathological effects of Doxorubicin on pancreas in male Albino rats Iraqi Journal of Veterinary Sciences histopathological effects doxorubicin pancreas male albino rats |
| title | Histopathological effects of Doxorubicin on pancreas in male Albino rats |
| title_full | Histopathological effects of Doxorubicin on pancreas in male Albino rats |
| title_fullStr | Histopathological effects of Doxorubicin on pancreas in male Albino rats |
| title_full_unstemmed | Histopathological effects of Doxorubicin on pancreas in male Albino rats |
| title_short | Histopathological effects of Doxorubicin on pancreas in male Albino rats |
| title_sort | histopathological effects of doxorubicin on pancreas in male albino rats |
| topic | histopathological effects doxorubicin pancreas male albino rats |
| url | https://vetmedmosul.com/article_116852_67a59e4ea88c559d3fe1cc5dc815e607.pdf |
| work_keys_str_mv | AT iaali histopathologicaleffectsofdoxorubicinonpancreasinmalealbinorats AT hjjumaa histopathologicaleffectsofdoxorubicinonpancreasinmalealbinorats AT hkhismael histopathologicaleffectsofdoxorubicinonpancreasinmalealbinorats |