Progress in CRISPR/Cas9 for CAR-T cell therapy of tumors

Progress in CRISPR/Cas9 for CAR-T cell therapy of tumors

CRISPR/Cas9 gene editing technology can effectively solve the problem of insufficient source of T cells in chimerical antigen receptor-T (CAR-T) therapy and enhance their anti-tumor abilities by knocking out the genes related to the suppression of T cells activity. The technology can also be used to...

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Bibliographic Details
Main Author:	WU Qi, WANG Shaobo
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2023-08-01
Series:	Jichu yixue yu linchuang
Subjects:	car-t cells\|crispr/cas9\|immunotherapy
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-8-1313.pdf

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