Transplantation of muscle-derived stem cells plus biodegradable fibrin glue restores the urethral sphincter in a pudendal nerve-transected rat model

Transplantation of muscle-derived stem cells plus biodegradable fibrin glue restores the urethral sphincter in a pudendal nerve-transected rat model

We investigated whether fibrin glue (FG) could promote urethral sphincter restoration in muscle-derived stem cell (MDSC)-based injection therapies in a pudendal nerve-transected (PNT) rat, which was used as a stress urinary incontinence (SUI) model. MDSCs were purified from the gastrocnemius muscles...

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Bibliographic Details
Main Authors: Y. Xu, Y.F. Song, Z.X. Lin
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2010-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Muscle-derived stem cells
Fibrin glue
Urinary incontinence
Cellular therapy
Pudendal nerve transection
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001100009

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