Granzymes in health and diseases: the good, the bad and the ugly
Granzymes are a family of serine proteases, composed of five human members: GA, B, H, M and K. They were first discovered in the 1980s within cytotoxic granules released during NK cell- and T cell-mediated killing. Through their various proteolytic activities, granzymes can trigger different pathway...
Autors principals: | , |
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Format: | Article |
Idioma: | English |
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Frontiers Media S.A.
2024-04-01
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Col·lecció: | Frontiers in Immunology |
Matèries: | |
Accés en línia: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1371743/full |