Granzymes in health and diseases: the good, the bad and the ugly

Granzymes are a family of serine proteases, composed of five human members: GA, B, H, M and K. They were first discovered in the 1980s within cytotoxic granules released during NK cell- and T cell-mediated killing. Through their various proteolytic activities, granzymes can trigger different pathway...

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Autors principals: Lavinia Cigalotto, Denis Martinvalet
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2024-04-01
Col·lecció:Frontiers in Immunology
Matèries:
Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1371743/full