Determination and Data Correlation of Solubility of Sofosbuvir Polymorphs in Ethyl Acetate + Toluene and Methyl <i>tert</i>-Butyl Ether Binary Solvents at the Temperature Range from 268.15 to 308.15 K
A gravimetric method was used to experimentally determine the (solid + liquid) equilibrium of sofosbuvir of crystalline forms A and B in both ethyl acetate + toluene and methyl <i>tert</i>-butyl ether (MTBE) + toluene binary solvents systems at atmosphere pressure. Experiments were carri...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | Crystals |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4352/10/3/209 |