Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency
Ocular pulse amplitude (OPA) is defined as the difference between maximum and minimum intraocular pressure (IOP) during a cardiac cycle. Average values of OPA range from 1 to 4 mmHg. The purpose of this investigation is to determine the source of an irregular IOP waveform with elevated OPA in a 48-y...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=1;spage=59;epage=61;aulast=Kassem |
| _version_ | 1819231026113675264 |
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| author | Jean B Kassem Steven E Katz Ashraf M Mahmoud Robert H Small Subha V Raman Cynthia J Roberts |
| author_facet | Jean B Kassem Steven E Katz Ashraf M Mahmoud Robert H Small Subha V Raman Cynthia J Roberts |
| author_sort | Jean B Kassem |
| collection | DOAJ |
| description | Ocular pulse amplitude (OPA) is defined as the difference between maximum and minimum intraocular pressure (IOP) during a cardiac cycle. Average values of OPA range from 1 to 4 mmHg. The purpose of this investigation is to determine the source of an irregular IOP waveform with elevated OPA in a 48-year-old male. Ocular pressure waveforms had an unusual shape consistent with early ventricular contraction. With a normal IOP, OPA was 9 mmHg, which is extraordinarily high. The subject was examined by a cardiologist and was determined to be in ventricular bigeminy. In addition, he had bounding carotid pulses and echocardiogram confirmed aortic insufficiency. After replacement of the aortic valve, the bigeminy resolved and the ocular pulse waveform became regular in appearance with an OPA of 1.6-2.0 mmHg. The ocular pressure waveform is a direct reflection of hemodynamics. Evaluating this waveform may provide an additional opportunity for screening subjects for cardiovascular anomalies and arrhythmias. |
| first_indexed | 2024-12-23T11:38:25Z |
| format | Article |
| id | doaj.art-7e554d4b769b4a0a88be8647592d7e9d |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-23T11:38:25Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-7e554d4b769b4a0a88be8647592d7e9d2022-12-21T17:48:35ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892015-01-01631596110.4103/0301-4738.151472Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiencyJean B KassemSteven E KatzAshraf M MahmoudRobert H SmallSubha V RamanCynthia J RobertsOcular pulse amplitude (OPA) is defined as the difference between maximum and minimum intraocular pressure (IOP) during a cardiac cycle. Average values of OPA range from 1 to 4 mmHg. The purpose of this investigation is to determine the source of an irregular IOP waveform with elevated OPA in a 48-year-old male. Ocular pressure waveforms had an unusual shape consistent with early ventricular contraction. With a normal IOP, OPA was 9 mmHg, which is extraordinarily high. The subject was examined by a cardiologist and was determined to be in ventricular bigeminy. In addition, he had bounding carotid pulses and echocardiogram confirmed aortic insufficiency. After replacement of the aortic valve, the bigeminy resolved and the ocular pulse waveform became regular in appearance with an OPA of 1.6-2.0 mmHg. The ocular pressure waveform is a direct reflection of hemodynamics. Evaluating this waveform may provide an additional opportunity for screening subjects for cardiovascular anomalies and arrhythmias.http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=1;spage=59;epage=61;aulast=KassemCup to disc ratiodisc areaglaucoma probability scoremoorfields regression analysisoptical coherence tomographyAntioxidant supplementationdiabetes mellitusfree oxygen radicals testnonproliferative diabetic retinopathyreactive oxygen speciesIn vivo confocal microscopy keratocyte densityprostaglandin analoguesChronic glaucoma patientseconomic burdensocioeconomic profileBevacizumabmacular edemarefractoryretinal vein occlusiontriamcinolone acetonideCorneal thicknessmenstrual cyclepachymetryrefractive surgeryCytokinesdiabetic retinopathypigment epithelium-derived factorvascular endothelial growth factorChoroidal metastasesintravitreal bevacizumabtranspupillary thermotherapyFundus examinationhalogen lightindirect ophthalmoscopelight emitting diodephoto-stress testAlgorithmcross-linkingIntacskeratoconusnormogramBibliometricsbiomedical researchjournal impact factorophthalmic researchsurgical researchAortic insufficiencyarrhythmiaocular pulse amplitudeventricular bigeminy |
| spellingShingle | Jean B Kassem Steven E Katz Ashraf M Mahmoud Robert H Small Subha V Raman Cynthia J Roberts Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency Indian Journal of Ophthalmology Cup to disc ratio disc area glaucoma probability score moorfields regression analysis optical coherence tomography Antioxidant supplementation diabetes mellitus free oxygen radicals test nonproliferative diabetic retinopathy reactive oxygen species In vivo confocal microscopy keratocyte density prostaglandin analogues Chronic glaucoma patients economic burden socioeconomic profile Bevacizumab macular edema refractory retinal vein occlusion triamcinolone acetonide Corneal thickness menstrual cycle pachymetry refractive surgery Cytokines diabetic retinopathy pigment epithelium-derived factor vascular endothelial growth factor Choroidal metastases intravitreal bevacizumab transpupillary thermotherapy Fundus examination halogen light indirect ophthalmoscope light emitting diode photo-stress test Algorithm cross-linking Intacs keratoconus normogram Bibliometrics biomedical research journal impact factor ophthalmic research surgical research Aortic insufficiency arrhythmia ocular pulse amplitude ventricular bigeminy |
| title | Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency |
| title_full | Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency |
| title_fullStr | Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency |
| title_full_unstemmed | Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency |
| title_short | Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency |
| title_sort | ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency |
| topic | Cup to disc ratio disc area glaucoma probability score moorfields regression analysis optical coherence tomography Antioxidant supplementation diabetes mellitus free oxygen radicals test nonproliferative diabetic retinopathy reactive oxygen species In vivo confocal microscopy keratocyte density prostaglandin analogues Chronic glaucoma patients economic burden socioeconomic profile Bevacizumab macular edema refractory retinal vein occlusion triamcinolone acetonide Corneal thickness menstrual cycle pachymetry refractive surgery Cytokines diabetic retinopathy pigment epithelium-derived factor vascular endothelial growth factor Choroidal metastases intravitreal bevacizumab transpupillary thermotherapy Fundus examination halogen light indirect ophthalmoscope light emitting diode photo-stress test Algorithm cross-linking Intacs keratoconus normogram Bibliometrics biomedical research journal impact factor ophthalmic research surgical research Aortic insufficiency arrhythmia ocular pulse amplitude ventricular bigeminy |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=1;spage=59;epage=61;aulast=Kassem |
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