A Novel Humanized Model of NASH and Its Treatment With META4, A Potent Agonist of METSummary

A Novel Humanized Model of NASH and Its Treatment With META4, A Potent Agonist of METSummary

Background & Aims: Nonalcoholic fatty liver disease is a frequent cause of hepatic dysfunction and is now a global epidemic. This ailment can progress to an advanced form called nonalcoholic steatohepatitis (NASH) and end-stage liver disease. Currently, the molecular basis of NASH pathogenes...

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Bibliographic Details
Main Authors: Jihong Ma, Xinping Tan, Yongkook Kwon, Evan R. Delgado, Arman Zarnegar, Marie C. DeFrances, Andrew W. Duncan, Reza Zarnegar
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
FAH Mice
Fatty Liver Disease
Hepatocyte Growth Factor
HGF
HGF antagonist
High-fat Diet
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21002216

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