Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5

Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5

RNA-binding proteins contribute to the formation of ribonucleoprotein (RNP) granules by phase transition, but regulatory mechanisms are not fully understood. Conserved fission yeast NDR (Nuclear Dbf2-Related) kinase Orb6 governs cell morphogenesis in part by spatially controlling Cdc42 GTPase. Here...

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Bibliographic Details
Main Authors: Illyce Nuñez, Marbelys Rodriguez Pino, David J Wiley, Maitreyi E Das, Chuan Chen, Tetsuya Goshima, Kazunori Kume, Dai Hirata, Takashi Toda, Fulvia Verde
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
polarized growth
NDR kinase
translational repression
P-body
RNP granule assembly
14-3-3 protein
Online Access:https://elifesciences.org/articles/14216

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