In vitro Bactericidal Activities of Combination Antibiotic Therapies Against Carbapenem-Resistant Klebsiella pneumoniae With Different Carbapenemases and Sequence Types

In vitro Bactericidal Activities of Combination Antibiotic Therapies Against Carbapenem-Resistant Klebsiella pneumoniae With Different Carbapenemases and Sequence Types

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is becoming increasingly problematic due to the limited effectiveness of new antimicrobials or other factors such as treatment cost. Thus, combination therapy remains a suitable treatment option. We aimed to evaluate the in vitro bactericidal activit...

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Bibliographic Details
Main Authors: Jocelyn Qi-Min Teo, Nazira Fauzi, Jayden Jun-Yuan Ho, Si Hui Tan, Shannon Jing-Yi Lee, Tze Peng Lim, Yiying Cai, Hong Yi Chang, Nurhayati Mohamed Yusoff, James Heng-Chiak Sim, Thuan Tong Tan, Rick Twee-Hee Ong, Andrea Lay-Hoon Kwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Microbiology
Subjects:
in vitro
bactericidal
combination
carbapenemase
enterobacterales
tigecycline
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.779988/full

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