An Emerging Animal Model for Querying the Role of Whole Genome Duplication in Development, Evolution, and Disease

An Emerging Animal Model for Querying the Role of Whole Genome Duplication in Development, Evolution, and Disease

Whole genome duplication (WGD) or polyploidization can occur at the cellular, tissue, and organismal levels. At the cellular level, tetraploidization has been proposed as a driver of aneuploidy and genome instability and correlates strongly with cancer progression, metastasis, and the development of...

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Bibliographic Details
Main Authors: Mara Schvarzstein, Fatema Alam, Muhammad Toure, Judith L. Yanowitz
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Developmental Biology
Subjects:
whole genome duplication
polyploidization
tetraploidy
polyploidy
aneuploidy
<i>Caenorhabditis</i>
Online Access:https://www.mdpi.com/2221-3759/11/2/26

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