Contribution of Multiple Inherited Variants to Autism Spectrum Disorder (ASD) in a Family with 3 Affected Siblings

Contribution of Multiple Inherited Variants to Autism Spectrum Disorder (ASD) in a Family with 3 Affected Siblings

Autism Spectrum Disorder (ASD) is the most common neurodevelopmental disorder in children and shows high heritability. However, how inherited variants contribute to ASD in multiplex families remains unclear. Using whole-genome sequencing (WGS) in a family with three affected children, we identified...

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Bibliographic Details
Main Authors:	Jasleen Dhaliwal, Ying Qiao, Kristina Calli, Sally Martell, Simone Race, Chieko Chijiwa, Armansa Glodjo, Steven Jones, Evica Rajcan-Separovic, Stephen W. Scherer, Suzanne Lewis
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Series:	Genes
Subjects:	Autism Spectrum Disorder (ASD) whole-genome sequencing (WGS) gene variants <i>RELN</i> gene <i>SHANK2</i> gene quantitative trait hypothesis
Online Access:	https://www.mdpi.com/2073-4425/12/7/1053

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