The NF-κB Pharmacopeia: Novel Strategies to Subdue an Intractable Target

The NF-κB Pharmacopeia: Novel Strategies to Subdue an Intractable Target

NF-κB transcription factors are major drivers of tumor initiation and progression. NF-κB signaling is constitutively activated by genetic alterations or environmental signals in many human cancers, where it contributes to almost all hallmarks of malignancy, including sustained proliferation, cell de...

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Bibliographic Details
Main Authors: Daniela Verzella, Jessica Cornice, Paola Arboretto, Davide Vecchiotti, Mauro Di Vito Nolfi, Daria Capece, Francesca Zazzeroni, Guido Franzoso
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
nuclear factor κB
NF-κB inhibitors
cancer therapy
targeted therapy
Online Access:https://www.mdpi.com/2227-9059/10/9/2233

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