Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification
Electrochemical immunosensors have attracted immense attention due to the ease of mass electrode production and the high compatibility of the miniature electric reader, which is beneficial for developing point-of-care diagnostic devices. Electrochemical immunosensors can be divided into label-free a...
| Autores principales: | , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
MDPI AG
2023-01-01
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| Colección: | Biosensors |
| Materias: | |
| Acceso en línea: | https://www.mdpi.com/2079-6374/13/1/125 |
| _version_ | 1827627981301874688 |
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| author | Avinash V. Police Patil Yu-Sheng Chuang Chenzhong Li Ching-Chou Wu |
| author_facet | Avinash V. Police Patil Yu-Sheng Chuang Chenzhong Li Ching-Chou Wu |
| author_sort | Avinash V. Police Patil |
| collection | DOAJ |
| description | Electrochemical immunosensors have attracted immense attention due to the ease of mass electrode production and the high compatibility of the miniature electric reader, which is beneficial for developing point-of-care diagnostic devices. Electrochemical immunosensors can be divided into label-free and label-based sensing strategies equipped with potentiometric, amperometric, voltammetric, or impedimetric detectors. Emerging nanomaterials are frequently used on electrochemical immunosensors as a highly rough and conductive interface of the electrodes or on nanocarriers of immobilizing capture antibodies, electroactive mediators, or catalyzers. Adopting nanomaterials can increase immunosensor characteristics with lower detection limits and better sensitivity. Recent research has shown innovative immobilization procedures of nanomaterials which meet the requirements of different electrochemical immunosensors. This review discusses the past five years of advances in nanomaterials (metal nanoparticles, metal nanostructures, carbon nanotubes, and graphene) integrated into the electrochemical immunosensor. Furthermore, the new tendency and endeavors of nanomaterial-based electrochemical immunosensors are discussed. |
| first_indexed | 2024-03-09T13:24:25Z |
| format | Article |
| id | doaj.art-7e5ee55ed2524933b457ae9a02464f0a |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T13:24:25Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-7e5ee55ed2524933b457ae9a02464f0a2023-11-30T21:25:52ZengMDPI AGBiosensors2079-63742023-01-0113112510.3390/bios13010125Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal AmplificationAvinash V. Police Patil0Yu-Sheng Chuang1Chenzhong Li2Ching-Chou Wu3Department of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung City 402, TaiwanDepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung City 402, TaiwanDepartment of Biochemistry and Molecular Biology, Tulane University, 1324 Tulane Ave., New Orleans, LA 70112, USADepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung City 402, TaiwanElectrochemical immunosensors have attracted immense attention due to the ease of mass electrode production and the high compatibility of the miniature electric reader, which is beneficial for developing point-of-care diagnostic devices. Electrochemical immunosensors can be divided into label-free and label-based sensing strategies equipped with potentiometric, amperometric, voltammetric, or impedimetric detectors. Emerging nanomaterials are frequently used on electrochemical immunosensors as a highly rough and conductive interface of the electrodes or on nanocarriers of immobilizing capture antibodies, electroactive mediators, or catalyzers. Adopting nanomaterials can increase immunosensor characteristics with lower detection limits and better sensitivity. Recent research has shown innovative immobilization procedures of nanomaterials which meet the requirements of different electrochemical immunosensors. This review discusses the past five years of advances in nanomaterials (metal nanoparticles, metal nanostructures, carbon nanotubes, and graphene) integrated into the electrochemical immunosensor. Furthermore, the new tendency and endeavors of nanomaterial-based electrochemical immunosensors are discussed.https://www.mdpi.com/2079-6374/13/1/125affinity reactionimmunosensorsnanomaterialselectrochemistry |
| spellingShingle | Avinash V. Police Patil Yu-Sheng Chuang Chenzhong Li Ching-Chou Wu Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification Biosensors affinity reaction immunosensors nanomaterials electrochemistry |
| title | Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification |
| title_full | Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification |
| title_fullStr | Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification |
| title_full_unstemmed | Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification |
| title_short | Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification |
| title_sort | recent advances in electrochemical immunosensors with nanomaterial assistance for signal amplification |
| topic | affinity reaction immunosensors nanomaterials electrochemistry |
| url | https://www.mdpi.com/2079-6374/13/1/125 |
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