Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models

Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models

Extracellular vesicles (EV) are considered as a potential tool for early disease diagnosis; however, factors modifying EV release remain partially unknown. By using patient-derived organoids that capture the cellular heterogeneity of epithelial tissues, here we studied the connection between the Wnt...

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Bibliographic Details
Main Authors: Gyöngyvér Orsolya Sándor, András Áron Soós, Péter Lörincz, Lívia Rojkó, Tünde Harkó, Levente Bogyó, Tamás Tölgyes, Attila Bursics, Edit I. Buzás, Judit Moldvay, Zoltán Wiener
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
lung adenocarcinoma
lung cancer
organoid
pancreatic ductal adenocarcinoma
exosome
CD133
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.670825/full

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