Septic shock in a woman with a hydatidiform mole: A case report
Hydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock. A 30-year-old multiparous woman with Basedow's disease presented with...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-07-01
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| Series: | Case Reports in Women's Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214911222000376 |
| _version_ | 1828292010752081920 |
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| author | Yuki Yoshimoto Tsuyoshi Murata Moeko Machida Yoshihiro Nozawa Soichi Nakamura Ryuji Yamauchi |
| author_facet | Yuki Yoshimoto Tsuyoshi Murata Moeko Machida Yoshihiro Nozawa Soichi Nakamura Ryuji Yamauchi |
| author_sort | Yuki Yoshimoto |
| collection | DOAJ |
| description | Hydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock. A 30-year-old multiparous woman with Basedow's disease presented with fever, amenorrhea, and vaginal bleeding. Transvaginal ultrasonography revealed an enlarged uterus with an intrauterine vesicular mass (74.3 × 93.0 mm). Human chorionic gonadotropin level was 994,000 mIU/mL. C-reactive protein was elevated, and blood cultures were positive (gram-negative rods), indicating infection. After administering antibiotics (tazobactam and piperacillin), blood pressure suddenly decreased (69/45 mmHg), requiring stabilization with noradrenaline and albumin. The uterine contents were naturally expelled, followed by dilatation and curettage after her vital signs and general condition gradually improved. The pathological diagnosis was a complete hydatidiform mole. Culture of the intrauterine contents revealed Escherichia coli, leading to the potentially fatal diagnosis of septic shock associated with a hydatidiform mole. |
| first_indexed | 2024-04-13T11:01:11Z |
| format | Article |
| id | doaj.art-7e6027ec451a4d339ca157b516fa15bd |
| institution | Directory Open Access Journal |
| issn | 2214-9112 |
| language | English |
| last_indexed | 2024-04-13T11:01:11Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Reports in Women's Health |
| spelling | doaj.art-7e6027ec451a4d339ca157b516fa15bd2022-12-22T02:49:24ZengElsevierCase Reports in Women's Health2214-91122022-07-0135e00417Septic shock in a woman with a hydatidiform mole: A case reportYuki Yoshimoto0Tsuyoshi Murata1Moeko Machida2Yoshihiro Nozawa3Soichi Nakamura4Ryuji Yamauchi5Department of Obstetrics and Gynecology, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajiro, Shirakawa, Fukushima 961-0005, Japan; Corresponding author.Department of Obstetrics and Gynecology, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajiro, Shirakawa, Fukushima 961-0005, JapanDepartment of General Medicine, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajiro, Shirakawa, Fukushima 961-0005, JapanDepartment of Diagnostic Pathology, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajiro, Shirakawa, Fukushima 961-0005, JapanDepartment of Obstetrics and Gynecology, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajiro, Shirakawa, Fukushima 961-0005, JapanDepartment of Obstetrics and Gynecology, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajiro, Shirakawa, Fukushima 961-0005, JapanHydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock. A 30-year-old multiparous woman with Basedow's disease presented with fever, amenorrhea, and vaginal bleeding. Transvaginal ultrasonography revealed an enlarged uterus with an intrauterine vesicular mass (74.3 × 93.0 mm). Human chorionic gonadotropin level was 994,000 mIU/mL. C-reactive protein was elevated, and blood cultures were positive (gram-negative rods), indicating infection. After administering antibiotics (tazobactam and piperacillin), blood pressure suddenly decreased (69/45 mmHg), requiring stabilization with noradrenaline and albumin. The uterine contents were naturally expelled, followed by dilatation and curettage after her vital signs and general condition gradually improved. The pathological diagnosis was a complete hydatidiform mole. Culture of the intrauterine contents revealed Escherichia coli, leading to the potentially fatal diagnosis of septic shock associated with a hydatidiform mole.http://www.sciencedirect.com/science/article/pii/S2214911222000376Hydatidiform moleSepsisSeptic shockVesicular patternUltrasound |
| spellingShingle | Yuki Yoshimoto Tsuyoshi Murata Moeko Machida Yoshihiro Nozawa Soichi Nakamura Ryuji Yamauchi Septic shock in a woman with a hydatidiform mole: A case report Case Reports in Women's Health Hydatidiform mole Sepsis Septic shock Vesicular pattern Ultrasound |
| title | Septic shock in a woman with a hydatidiform mole: A case report |
| title_full | Septic shock in a woman with a hydatidiform mole: A case report |
| title_fullStr | Septic shock in a woman with a hydatidiform mole: A case report |
| title_full_unstemmed | Septic shock in a woman with a hydatidiform mole: A case report |
| title_short | Septic shock in a woman with a hydatidiform mole: A case report |
| title_sort | septic shock in a woman with a hydatidiform mole a case report |
| topic | Hydatidiform mole Sepsis Septic shock Vesicular pattern Ultrasound |
| url | http://www.sciencedirect.com/science/article/pii/S2214911222000376 |
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