Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma

Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma

Higher oxidant stress capacity could promote invasion and metastasis. A previous study showed hepatocellular carcinoma (HCC) expressed more Nrf2 than para-carcinoma tissue. The chemotherapeutics such as epirubicin (EPI) could increase Nrf2 expression, while Camptothecin (CPT) could inhibit tumor gro...

Full description

Bibliographic Details
Main Authors: Qian Liu, Shanshan Zhao, Fanguang Meng, Hankang Wang, Liwei Sun, Guijie Li, Feng Gao, Feng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
metastasis
reactive oxygen species
Nrf2
camptothecin
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.661157/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.661157/full

Similar Items