Fulminant hepatitis during self-medication with conjugated linoleic acid

The present report describes a 63-year-old female who presented with fulminant hepatic failure requiring liver transplantation caused by a weight loss dietary supplement containing conjugated linoleic acid (CLA). Thorough investigation, including liver biopsy, revealed no other cause of hepatotoxici...

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Main Authors: Rita Nortadas, José Barata
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119310348
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author Rita Nortadas
José Barata
author_facet Rita Nortadas
José Barata
author_sort Rita Nortadas
collection DOAJ
description The present report describes a 63-year-old female who presented with fulminant hepatic failure requiring liver transplantation caused by a weight loss dietary supplement containing conjugated linoleic acid (CLA). Thorough investigation, including liver biopsy, revealed no other cause of hepatotoxicity. In the last few years, a considerable number of reports have been published on toxic hepatitis, associated with non-conventional products, attributed with weight-reducing properties. We emphasize the importance of taking a cautious approach when consuming herbal supplements for the purpose of weight loss, as all that is “natural” may not always be healthy. Only one report of CLA-induced toxic hepatitis is related in the medical literature.
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spelling doaj.art-7e647c04da5847f1a20e032d316fc8c62022-12-21T20:07:58ZengElsevierAnnals of Hepatology1665-26812012-03-01112265267Fulminant hepatitis during self-medication with conjugated linoleic acidRita Nortadas0José Barata1Medical Department, Garcia de Orta Hospital, Almada, Portugal; Correspondence and reprint request:Medical Department, Garcia de Orta Hospital, Almada, PortugalThe present report describes a 63-year-old female who presented with fulminant hepatic failure requiring liver transplantation caused by a weight loss dietary supplement containing conjugated linoleic acid (CLA). Thorough investigation, including liver biopsy, revealed no other cause of hepatotoxicity. In the last few years, a considerable number of reports have been published on toxic hepatitis, associated with non-conventional products, attributed with weight-reducing properties. We emphasize the importance of taking a cautious approach when consuming herbal supplements for the purpose of weight loss, as all that is “natural” may not always be healthy. Only one report of CLA-induced toxic hepatitis is related in the medical literature.http://www.sciencedirect.com/science/article/pii/S1665268119310348Conjugated linoleic acidToxic hepatitisFulminant hepatitisLiver transplantation
spellingShingle Rita Nortadas
José Barata
Fulminant hepatitis during self-medication with conjugated linoleic acid
Annals of Hepatology
Conjugated linoleic acid
Toxic hepatitis
Fulminant hepatitis
Liver transplantation
title Fulminant hepatitis during self-medication with conjugated linoleic acid
title_full Fulminant hepatitis during self-medication with conjugated linoleic acid
title_fullStr Fulminant hepatitis during self-medication with conjugated linoleic acid
title_full_unstemmed Fulminant hepatitis during self-medication with conjugated linoleic acid
title_short Fulminant hepatitis during self-medication with conjugated linoleic acid
title_sort fulminant hepatitis during self medication with conjugated linoleic acid
topic Conjugated linoleic acid
Toxic hepatitis
Fulminant hepatitis
Liver transplantation
url http://www.sciencedirect.com/science/article/pii/S1665268119310348
work_keys_str_mv AT ritanortadas fulminanthepatitisduringselfmedicationwithconjugatedlinoleicacid
AT josebarata fulminanthepatitisduringselfmedicationwithconjugatedlinoleicacid