Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model

Abstract Background Type 2 Diabetes mellitus (T2DM) has become a major lifestyle disease endangering human health worldwide. Patients with T2DM face varying degrees of loneliness, which adversely affects their family and the larger society. This study investigates the serial multiple mediating roles...

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Main Authors: Yu Zhang, Xiangning Li, Yaxin Bi, Yinshi Kan, Hongyuan Liu, Lin Liu, Yan Zou, Ning Zhang, Li Fang, Weijuan Gong
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-023-05122-y
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author Yu Zhang
Xiangning Li
Yaxin Bi
Yinshi Kan
Hongyuan Liu
Lin Liu
Yan Zou
Ning Zhang
Li Fang
Weijuan Gong
author_facet Yu Zhang
Xiangning Li
Yaxin Bi
Yinshi Kan
Hongyuan Liu
Lin Liu
Yan Zou
Ning Zhang
Li Fang
Weijuan Gong
author_sort Yu Zhang
collection DOAJ
description Abstract Background Type 2 Diabetes mellitus (T2DM) has become a major lifestyle disease endangering human health worldwide. Patients with T2DM face varying degrees of loneliness, which adversely affects their family and the larger society. This study investigates the serial multiple mediating roles of depression and self-perceived burden between family function and loneliness in the T2DM population of China. Methods In total, 260 T2DM patients were included. They rated themselves based on UCLA Loneliness Scale, Self-Rating Depression Scale, Self-Rating Anxiety Scale, Family Care Index, and Self-Perceived Burden Scale. Pearson and Spearman correlation analyses were conducted to clarify the association among variables. The SPSS macro-PROCESS program was used for a series of multiple mediation analyses. Results Family function, depression, self-perceived burden, and loneliness were significantly correlated (P < 0.01). Family function not only has a direct negative impact (effect = -2.809; SE = 0.213; 95%CI: LL = -3.228, UL = -2.390) on loneliness, but also has an indirect impact on loneliness through the independent mediating role of depression (effect = -0.862; SE = 0.165; 95%CI: LL = -1.202, UL = -0.567) and self-perceived burden (effect = -0.288; SE = 0.107; 95%CI: LL = -0.525, UL = -0.114) and the chain mediating role of depression and self-perceived burden (effect = -0.202; SE = 0.066; 95%CI: LL = -0.342, UL = -0.088). Conclusions Diversified interventions aimed at improving family function of T2DM patients would help in reducing the level of depression and self-perceived burden, and ultimately reducing loneliness.
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spelling doaj.art-7e66c84b6f2d4043850ef16bdc1b46092023-11-20T10:29:45ZengBMCBMC Psychiatry1471-244X2023-08-012311910.1186/s12888-023-05122-yEffects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation modelYu Zhang0Xiangning Li1Yaxin Bi2Yinshi Kan3Hongyuan Liu4Lin Liu5Yan Zou6Ning Zhang7Li Fang8Weijuan Gong9School of Nursing, Yangzhou UniversitySchool of Nursing, Yangzhou UniversityNorthern Jiangsu People’s HospitalSchool of Nursing, Yangzhou UniversitySchool of Nursing, Yangzhou UniversitySchool of Nursing, Yangzhou UniversitySchool of Nursing, Yangzhou UniversitySchool of Nursing, Yangzhou UniversityAffiliated Hospital of Yangzhou UniversityDepartment of Basic Medicine, School of Medicine, Yangzhou UniversityAbstract Background Type 2 Diabetes mellitus (T2DM) has become a major lifestyle disease endangering human health worldwide. Patients with T2DM face varying degrees of loneliness, which adversely affects their family and the larger society. This study investigates the serial multiple mediating roles of depression and self-perceived burden between family function and loneliness in the T2DM population of China. Methods In total, 260 T2DM patients were included. They rated themselves based on UCLA Loneliness Scale, Self-Rating Depression Scale, Self-Rating Anxiety Scale, Family Care Index, and Self-Perceived Burden Scale. Pearson and Spearman correlation analyses were conducted to clarify the association among variables. The SPSS macro-PROCESS program was used for a series of multiple mediation analyses. Results Family function, depression, self-perceived burden, and loneliness were significantly correlated (P < 0.01). Family function not only has a direct negative impact (effect = -2.809; SE = 0.213; 95%CI: LL = -3.228, UL = -2.390) on loneliness, but also has an indirect impact on loneliness through the independent mediating role of depression (effect = -0.862; SE = 0.165; 95%CI: LL = -1.202, UL = -0.567) and self-perceived burden (effect = -0.288; SE = 0.107; 95%CI: LL = -0.525, UL = -0.114) and the chain mediating role of depression and self-perceived burden (effect = -0.202; SE = 0.066; 95%CI: LL = -0.342, UL = -0.088). Conclusions Diversified interventions aimed at improving family function of T2DM patients would help in reducing the level of depression and self-perceived burden, and ultimately reducing loneliness.https://doi.org/10.1186/s12888-023-05122-yType 2 diabetes mellitusLonelinessFamily functionDepressionSelf-perceived burdenSerial multiple mediation effect
spellingShingle Yu Zhang
Xiangning Li
Yaxin Bi
Yinshi Kan
Hongyuan Liu
Lin Liu
Yan Zou
Ning Zhang
Li Fang
Weijuan Gong
Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model
BMC Psychiatry
Type 2 diabetes mellitus
Loneliness
Family function
Depression
Self-perceived burden
Serial multiple mediation effect
title Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model
title_full Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model
title_fullStr Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model
title_full_unstemmed Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model
title_short Effects of family function, depression, and self-perceived burden on loneliness in patients with type 2 diabetes mellitus: a serial multiple mediation model
title_sort effects of family function depression and self perceived burden on loneliness in patients with type 2 diabetes mellitus a serial multiple mediation model
topic Type 2 diabetes mellitus
Loneliness
Family function
Depression
Self-perceived burden
Serial multiple mediation effect
url https://doi.org/10.1186/s12888-023-05122-y
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