Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems
Multicomponent reactions, conducted in a domino, sequential or consecutive fashion, have not only considerably enhanced synthetic efficiency as one-pot methodology, but they have also become an enabling tool for interdisciplinary research. The highly diversity-oriented nature of the synthetic concep...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2023.1124209/full |
| _version_ | 1827987789513228288 |
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| author | Larissa Brandner Thomas J. J. Müller |
| author_facet | Larissa Brandner Thomas J. J. Müller |
| author_sort | Larissa Brandner |
| collection | DOAJ |
| description | Multicomponent reactions, conducted in a domino, sequential or consecutive fashion, have not only considerably enhanced synthetic efficiency as one-pot methodology, but they have also become an enabling tool for interdisciplinary research. The highly diversity-oriented nature of the synthetic concept allows accessing huge structural and functional space. Already some decades ago this has been recognized for life sciences, in particular, lead finding and exploration in pharma and agricultural chemistry. The quest for novel functional materials has also opened the field for diversity-oriented syntheses of functional π-systems, i.e. dyes for photonic and electronic applications based on their electronic properties. This review summarizes recent developments in MCR syntheses of functional chromophores highlighting syntheses following either the framework forming scaffold approach by establishing connectivity between chromophores or the chromogenic chromophore approach by de novo formation of chromophore of interest. Both approaches warrant rapid access to molecular functional π-systems, i.e. chromophores, fluorophores, and electrophores for various applications. |
| first_indexed | 2024-04-09T23:53:35Z |
| format | Article |
| id | doaj.art-7e6b0db377d242a9b9a74830009233bf |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-09T23:53:35Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-7e6b0db377d242a9b9a74830009233bf2023-03-17T04:47:22ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462023-03-011110.3389/fchem.2023.11242091124209Multicomponent synthesis of chromophores – The one-pot approach to functional π-systemsLarissa BrandnerThomas J. J. MüllerMulticomponent reactions, conducted in a domino, sequential or consecutive fashion, have not only considerably enhanced synthetic efficiency as one-pot methodology, but they have also become an enabling tool for interdisciplinary research. The highly diversity-oriented nature of the synthetic concept allows accessing huge structural and functional space. Already some decades ago this has been recognized for life sciences, in particular, lead finding and exploration in pharma and agricultural chemistry. The quest for novel functional materials has also opened the field for diversity-oriented syntheses of functional π-systems, i.e. dyes for photonic and electronic applications based on their electronic properties. This review summarizes recent developments in MCR syntheses of functional chromophores highlighting syntheses following either the framework forming scaffold approach by establishing connectivity between chromophores or the chromogenic chromophore approach by de novo formation of chromophore of interest. Both approaches warrant rapid access to molecular functional π-systems, i.e. chromophores, fluorophores, and electrophores for various applications.https://www.frontiersin.org/articles/10.3389/fchem.2023.1124209/fullabsorptionchromophoresdiversity-oriented synthesisdonor-acceptor systemsfluorescencemulticomponent reactions |
| spellingShingle | Larissa Brandner Thomas J. J. Müller Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems Frontiers in Chemistry absorption chromophores diversity-oriented synthesis donor-acceptor systems fluorescence multicomponent reactions |
| title | Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems |
| title_full | Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems |
| title_fullStr | Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems |
| title_full_unstemmed | Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems |
| title_short | Multicomponent synthesis of chromophores – The one-pot approach to functional π-systems |
| title_sort | multicomponent synthesis of chromophores the one pot approach to functional π systems |
| topic | absorption chromophores diversity-oriented synthesis donor-acceptor systems fluorescence multicomponent reactions |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2023.1124209/full |
| work_keys_str_mv | AT larissabrandner multicomponentsynthesisofchromophorestheonepotapproachtofunctionalpsystems AT thomasjjmuller multicomponentsynthesisofchromophorestheonepotapproachtofunctionalpsystems |