The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. It is linked to genetic and environmental factors such as nutrition. Insulin resistance (IR) is one of the major pathological changes in PCOS. This study aimed to determine the relationship between I...

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Main Authors: Mahboobe Gholami, Saeideh Ziaei, Anoshirvan Kazemnejad, Maryam Movahedinejad
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Sciences and Health Services 2023-05-01
Series:Journal of Nutrition and Food Security
Subjects:
Online Access:http://jnfs.ssu.ac.ir/article-1-532-en.html
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author Mahboobe Gholami
Saeideh Ziaei
Anoshirvan Kazemnejad
Maryam Movahedinejad
author_facet Mahboobe Gholami
Saeideh Ziaei
Anoshirvan Kazemnejad
Maryam Movahedinejad
author_sort Mahboobe Gholami
collection DOAJ
description Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. It is linked to genetic and environmental factors such as nutrition. Insulin resistance (IR) is one of the major pathological changes in PCOS. This study aimed to determine the relationship between IR and macronutrient intake in PCOS subgroups. Methods: This case-control study was performed on 151 women with PCOS and were divided into four groups according to the Rotterdam diagnostic criteria: A=41, B=33, C=40, and D=37, and 31 women were also in the control group and did not have this syndrome. All macronutrients were assessed with a 168-item food frequency questionnaire (FFQ). Results: There was a significant relationship between HOMA-IR and some dietary components  (Increased calorie in group A, increased total fat intake in group C, lower intake of unsaturated fats (PUFA and MUFA) in group D and higher intake of saturated fat (SFA) and protein intake in the control group). There was no correlation in subgroup B (ovulatory phenotype). Conclusion: Due to the significant relationship between IR and some dietary components in PCOS subtypes, it is recommended to maintain a balance in carbohydrate and fatty acids intake, and increase dietary fiber to improve health parameters in PCOS subjects.
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spelling doaj.art-7e6eaaf889814d7b82c3c50384b801c02023-05-06T06:48:59ZengShahid Sadoughi University of Medical Sciences and Health ServicesJournal of Nutrition and Food Security2476-74172476-74252023-05-0182202211The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary SyndromeMahboobe Gholami0Saeideh Ziaei1Anoshirvan Kazemnejad2Maryam Movahedinejad3 Department of Midwifery, School of Nursing and Midwifery, Neyshabur University of Medical Sciences, Neyshabur, Iran Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tehran Tarbiat Modares University, Tehran, Iran Department of Biostatistics, Faculty of Medical Sciences, Tehran Tarbiat Modares University, Tehran, Iran Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tehran Tarbiat Modares University, Tehran, Iran Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. It is linked to genetic and environmental factors such as nutrition. Insulin resistance (IR) is one of the major pathological changes in PCOS. This study aimed to determine the relationship between IR and macronutrient intake in PCOS subgroups. Methods: This case-control study was performed on 151 women with PCOS and were divided into four groups according to the Rotterdam diagnostic criteria: A=41, B=33, C=40, and D=37, and 31 women were also in the control group and did not have this syndrome. All macronutrients were assessed with a 168-item food frequency questionnaire (FFQ). Results: There was a significant relationship between HOMA-IR and some dietary components  (Increased calorie in group A, increased total fat intake in group C, lower intake of unsaturated fats (PUFA and MUFA) in group D and higher intake of saturated fat (SFA) and protein intake in the control group). There was no correlation in subgroup B (ovulatory phenotype). Conclusion: Due to the significant relationship between IR and some dietary components in PCOS subtypes, it is recommended to maintain a balance in carbohydrate and fatty acids intake, and increase dietary fiber to improve health parameters in PCOS subjects.http://jnfs.ssu.ac.ir/article-1-532-en.htmlmacronutrientpcosinsulin resistance
spellingShingle Mahboobe Gholami
Saeideh Ziaei
Anoshirvan Kazemnejad
Maryam Movahedinejad
The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome
Journal of Nutrition and Food Security
macronutrient
pcos
insulin resistance
title The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome
title_full The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome
title_fullStr The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome
title_full_unstemmed The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome
title_short The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome
title_sort relationship between macronutrient intake and insulin resistance in polycystic ovary syndrome
topic macronutrient
pcos
insulin resistance
url http://jnfs.ssu.ac.ir/article-1-532-en.html
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