Surveillance for Adenoviruses in Bats in Italy
Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-06-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/11/6/523 |
| _version_ | 1819153129372909568 |
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| author | Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli |
| author_facet | Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli |
| author_sort | Georgia Diakoudi |
| collection | DOAJ |
| description | Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a <i>Pipistrellus kuhlii</i>, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the <i>Pipistrellus pipistrellus</i> strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts. |
| first_indexed | 2024-12-22T15:00:17Z |
| format | Article |
| id | doaj.art-7e7b04cb8ef54520a18c4994b51b0914 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-12-22T15:00:17Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-7e7b04cb8ef54520a18c4994b51b09142022-12-21T18:22:08ZengMDPI AGViruses1999-49152019-06-0111652310.3390/v11060523v11060523Surveillance for Adenoviruses in Bats in ItalyGeorgia Diakoudi0Gianvito Lanave1Ana Moreno2Chiara Chiapponi3Enrica Sozzi4Alice Prosperi5Vittorio Larocca6Michele Losurdo7Nicola Decaro8Vito Martella9Antonio Lavazza10Davide Lelli11Dipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, ItalyDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, ItalyDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, ItalyDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, ItalyDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, ItalyDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, S.p per Casamassima km 3, 70010 Valenzano, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, ItalyIstituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Via Bianchi 9, 25124 Brescia, ItalyAdenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a <i>Pipistrellus kuhlii</i>, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the <i>Pipistrellus pipistrellus</i> strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts.https://www.mdpi.com/1999-4915/11/6/523batadenovirusmastadenovirusaviadenovirussequenceNGSItalyphylogenetic analysis |
| spellingShingle | Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli Surveillance for Adenoviruses in Bats in Italy Viruses bat adenovirus mastadenovirus aviadenovirus sequence NGS Italy phylogenetic analysis |
| title | Surveillance for Adenoviruses in Bats in Italy |
| title_full | Surveillance for Adenoviruses in Bats in Italy |
| title_fullStr | Surveillance for Adenoviruses in Bats in Italy |
| title_full_unstemmed | Surveillance for Adenoviruses in Bats in Italy |
| title_short | Surveillance for Adenoviruses in Bats in Italy |
| title_sort | surveillance for adenoviruses in bats in italy |
| topic | bat adenovirus mastadenovirus aviadenovirus sequence NGS Italy phylogenetic analysis |
| url | https://www.mdpi.com/1999-4915/11/6/523 |
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