Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis

This retrospective cohort study described changes in all-cause healthcare resource utilization (HCRU) and associated costs in dementia patients newly diagnosed with psychosis. Dementia and incident psychosis were identified using diagnostic and pharmacy claims using a Medicare 20% random sample data...

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Main Authors: Nazia Rashid, James B. Wetmore, Muna Irfan, Victor Abler
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Geriatrics
Subjects:
Online Access:https://www.mdpi.com/2308-3417/7/2/29
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author Nazia Rashid
James B. Wetmore
Muna Irfan
Victor Abler
author_facet Nazia Rashid
James B. Wetmore
Muna Irfan
Victor Abler
author_sort Nazia Rashid
collection DOAJ
description This retrospective cohort study described changes in all-cause healthcare resource utilization (HCRU) and associated costs in dementia patients newly diagnosed with psychosis. Dementia and incident psychosis were identified using diagnostic and pharmacy claims using a Medicare 20% random sample dataset. All-cause HCRU and unweighted and weighted (by person-years of follow-up) HCRU-associated costs were evaluated in the year prior to and the 4 years following diagnosis of psychosis. In 49,509 dementia patients with psychosis, physician visits per patient per year increased from a mean of 26.7 (standard deviation (SD) 20.0) prior to psychosis to 38.4 (SD 41.9) post-psychosis diagnosis. The number of inpatient stay claims increased from 1.0 (SD 1.4) to 1.7 (SD 5.8). Mean unweighted costs for inpatient stays and home healthcare/hospice during 2008–2016 were USD 9989 and USD 3279 prior to a diagnosis of psychosis but increased to USD 25,982 and USD 9901 (weighted: USD 11,779 and USD 6709), respectively, in the year after a psychosis diagnosis. This pattern of a sharp increase in mean costs was also observed in costs adjusted to 2015 USD, and in both unweighted and weighted total and psychosis-related costs. These results indicate the importance of identifying newly diagnosed psychosis in dementia patients as well as the pressing need for management strategies and treatments that can reduce HCRU and costs.
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spelling doaj.art-7e7b1ae539b94085b46f0f37319b23b52023-12-01T20:58:04ZengMDPI AGGeriatrics2308-34172022-03-01722910.3390/geriatrics7020029Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related PsychosisNazia Rashid0James B. Wetmore1Muna Irfan2Victor Abler3Acadia Pharmaceuticals Inc., San Diego, CA 92130, USADivision of Nephrology, Hennepin County Medical Center, Minneapolis, MN 55415, USAVeterans Affairs Medical Center, University of Minnesota, Minneapolis, MN 55417, USAAcadia Pharmaceuticals Inc., San Diego, CA 92130, USAThis retrospective cohort study described changes in all-cause healthcare resource utilization (HCRU) and associated costs in dementia patients newly diagnosed with psychosis. Dementia and incident psychosis were identified using diagnostic and pharmacy claims using a Medicare 20% random sample dataset. All-cause HCRU and unweighted and weighted (by person-years of follow-up) HCRU-associated costs were evaluated in the year prior to and the 4 years following diagnosis of psychosis. In 49,509 dementia patients with psychosis, physician visits per patient per year increased from a mean of 26.7 (standard deviation (SD) 20.0) prior to psychosis to 38.4 (SD 41.9) post-psychosis diagnosis. The number of inpatient stay claims increased from 1.0 (SD 1.4) to 1.7 (SD 5.8). Mean unweighted costs for inpatient stays and home healthcare/hospice during 2008–2016 were USD 9989 and USD 3279 prior to a diagnosis of psychosis but increased to USD 25,982 and USD 9901 (weighted: USD 11,779 and USD 6709), respectively, in the year after a psychosis diagnosis. This pattern of a sharp increase in mean costs was also observed in costs adjusted to 2015 USD, and in both unweighted and weighted total and psychosis-related costs. These results indicate the importance of identifying newly diagnosed psychosis in dementia patients as well as the pressing need for management strategies and treatments that can reduce HCRU and costs.https://www.mdpi.com/2308-3417/7/2/29dementiahallucinationsdelusionspsychosiseconomic burdenMedicare
spellingShingle Nazia Rashid
James B. Wetmore
Muna Irfan
Victor Abler
Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis
Geriatrics
dementia
hallucinations
delusions
psychosis
economic burden
Medicare
title Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis
title_full Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis
title_fullStr Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis
title_full_unstemmed Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis
title_short Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis
title_sort economic evaluation of healthcare resource utilization and costs for newly diagnosed dementia related psychosis
topic dementia
hallucinations
delusions
psychosis
economic burden
Medicare
url https://www.mdpi.com/2308-3417/7/2/29
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AT munairfan economicevaluationofhealthcareresourceutilizationandcostsfornewlydiagnoseddementiarelatedpsychosis
AT victorabler economicevaluationofhealthcareresourceutilizationandcostsfornewlydiagnoseddementiarelatedpsychosis