Diabetic Macular Edema: Traditional and Novel Treatment
Diabetes is one of the leading public health problems worldwide. Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. Ideal metabolic control of diabetes is the primary goal of treatment and the basic way of preventing and stopping the progression of DME. Although...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2017-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/271961 |
| _version_ | 1827283028448116736 |
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| author | Martina Tomić Romano Vrabec Tamara Poljičanin Spomenka Ljubić Lea Duvnjak |
| author_facet | Martina Tomić Romano Vrabec Tamara Poljičanin Spomenka Ljubić Lea Duvnjak |
| author_sort | Martina Tomić |
| collection | DOAJ |
| description | Diabetes is one of the leading public health problems worldwide. Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. Ideal metabolic control of diabetes is the primary goal of treatment and the basic way of preventing and stopping the progression of DME. Although laser photocoagulation has been the standard treatment of DME for nearly three decades, superior outcomes can be achieved with novel, intravitreal anti-VEGF and steroid therapy. Novel treatment option for DME depends on visual acuity and location/extent of macular thickening based on optical coherence tomography scans. According to the International Clinical Classification Scale, DME is divided into no center-involving DME and center-involving DME (CI-DME). New guidelines recommend intravitreal treatment as the treatment of choice for patients with CI-DME and moderate visual impairment. Patients with no CI-DME and mild visual impairment should be treated with modified ETDRS laser photocoagulation and closely observed. Vitrectomy is the treatment of choice for patients with a tractional component of DME. Nowadays, traditional treatment goal of preventing blindness in patients with DME has been changed by the new goal aiming to restore impaired vision, prevent further vision loss and improve visual function. Therefore, many trials addressing this new concept have been underway worldwide. |
| first_indexed | 2024-04-24T09:28:57Z |
| format | Article |
| id | doaj.art-7e7b6d7c950d44c5a37ce4f60ff965cb |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:28:57Z |
| publishDate | 2017-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-7e7b6d7c950d44c5a37ce4f60ff965cb2024-04-15T14:16:26ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512017-01-0156.1.12413210.20471/acc.2017.56.01.18Diabetic Macular Edema: Traditional and Novel TreatmentMartina Tomić0Romano Vrabec1Tamara Poljičanin2Spomenka Ljubić3Lea Duvnjak4Department of Ophthalmology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University HospitalDepartment of Ophthalmology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University HospitalCroatian National Institute of Public HealthDepartment of Diabetes and Endocrinology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, Zagreb, CroatiaDepartment of Diabetes and Endocrinology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, Zagreb, CroatiaDiabetes is one of the leading public health problems worldwide. Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. Ideal metabolic control of diabetes is the primary goal of treatment and the basic way of preventing and stopping the progression of DME. Although laser photocoagulation has been the standard treatment of DME for nearly three decades, superior outcomes can be achieved with novel, intravitreal anti-VEGF and steroid therapy. Novel treatment option for DME depends on visual acuity and location/extent of macular thickening based on optical coherence tomography scans. According to the International Clinical Classification Scale, DME is divided into no center-involving DME and center-involving DME (CI-DME). New guidelines recommend intravitreal treatment as the treatment of choice for patients with CI-DME and moderate visual impairment. Patients with no CI-DME and mild visual impairment should be treated with modified ETDRS laser photocoagulation and closely observed. Vitrectomy is the treatment of choice for patients with a tractional component of DME. Nowadays, traditional treatment goal of preventing blindness in patients with DME has been changed by the new goal aiming to restore impaired vision, prevent further vision loss and improve visual function. Therefore, many trials addressing this new concept have been underway worldwide.https://hrcak.srce.hr/file/271961Diabetes mellitusMacular edemaLaser photocoagulationVitrectomy |
| spellingShingle | Martina Tomić Romano Vrabec Tamara Poljičanin Spomenka Ljubić Lea Duvnjak Diabetic Macular Edema: Traditional and Novel Treatment Acta Clinica Croatica Diabetes mellitus Macular edema Laser photocoagulation Vitrectomy |
| title | Diabetic Macular Edema: Traditional and Novel Treatment |
| title_full | Diabetic Macular Edema: Traditional and Novel Treatment |
| title_fullStr | Diabetic Macular Edema: Traditional and Novel Treatment |
| title_full_unstemmed | Diabetic Macular Edema: Traditional and Novel Treatment |
| title_short | Diabetic Macular Edema: Traditional and Novel Treatment |
| title_sort | diabetic macular edema traditional and novel treatment |
| topic | Diabetes mellitus Macular edema Laser photocoagulation Vitrectomy |
| url | https://hrcak.srce.hr/file/271961 |
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