Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit
Objective: For many years in herbal medicine the antihypertensive and lowering blood lipid properties of Achillea wilhelmsii (A. wilhelmsii) have been suggested. In the present study the impacts of the plant extract on rabbit’s blood pressure and heart rate have been investigated. Materials and Meth...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2011-07-01
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| Series: | Avicenna Journal of Phytomedicine |
| Subjects: | |
| Online Access: | http://ajp.mums.ac.ir/pdf_121_6021025c5bf914e80846032682916fec.html |
| _version_ | 1828278912004653056 |
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| author | Saeed Niazmand M. Esparham S. A. Rezaee F. Harandizadeh |
| author_facet | Saeed Niazmand M. Esparham S. A. Rezaee F. Harandizadeh |
| author_sort | Saeed Niazmand |
| collection | DOAJ |
| description | Objective: For many years in herbal medicine the antihypertensive and lowering blood lipid properties of Achillea wilhelmsii (A. wilhelmsii) have been suggested. In the present study the impacts of the plant extract on rabbit’s blood pressure and heart rate have been investigated.
Materials and Methods: Twelve NWZ rabbits weighed 2-3 kg were randomly divided into two groups of 6 rabbits. The test group received A. wilhelmsii extract (20, 40 and 80 mg/kg) and the control group received normal saline by jugular vein cannula. Blood pressure and heart rate were measured via carotid cannula using pressure transducer connected to a power lab system.
Results: The blood pressure was significantly decreased (16.7± 1.4 mmHg) in 80 mg/kg dose of the extract (p |
| first_indexed | 2024-04-13T07:35:42Z |
| format | Article |
| id | doaj.art-7e7b87ea14b848108d1416546c22ed7d |
| institution | Directory Open Access Journal |
| issn | 2228-7930 2228-7949 |
| language | English |
| last_indexed | 2024-04-13T07:35:42Z |
| publishDate | 2011-07-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Avicenna Journal of Phytomedicine |
| spelling | doaj.art-7e7b87ea14b848108d1416546c22ed7d2022-12-22T02:56:09ZengMashhad University of Medical SciencesAvicenna Journal of Phytomedicine2228-79302228-79492011-07-01115156121Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbitSaeed Niazmand0M. Esparham1S. A. Rezaee2F. Harandizadeh3Department of Physiology and Cardiovascular Research Center, School of Medicine Mashhad University of Medical Sciences Mashhad, I. R. IranDepartment of Biology, School of Sciences, Islamic Azad University, Mashhad Branch, I. R. IranDepartment of Immunology, School of Medicine, Mashhad University of Medical Sciences Mashhad, I. R. IranDepartment of Biology, School of Sciences, Ferdowsi University. Mashhad, I. R. IranObjective: For many years in herbal medicine the antihypertensive and lowering blood lipid properties of Achillea wilhelmsii (A. wilhelmsii) have been suggested. In the present study the impacts of the plant extract on rabbit’s blood pressure and heart rate have been investigated. Materials and Methods: Twelve NWZ rabbits weighed 2-3 kg were randomly divided into two groups of 6 rabbits. The test group received A. wilhelmsii extract (20, 40 and 80 mg/kg) and the control group received normal saline by jugular vein cannula. Blood pressure and heart rate were measured via carotid cannula using pressure transducer connected to a power lab system. Results: The blood pressure was significantly decreased (16.7± 1.4 mmHg) in 80 mg/kg dose of the extract (phttp://ajp.mums.ac.ir/pdf_121_6021025c5bf914e80846032682916fec.htmlAchillea wilhelmsiiheart rateBlood pressureRabbit |
| spellingShingle | Saeed Niazmand M. Esparham S. A. Rezaee F. Harandizadeh Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit Avicenna Journal of Phytomedicine Achillea wilhelmsii heart rate Blood pressure Rabbit |
| title | Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit |
| title_full | Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit |
| title_fullStr | Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit |
| title_full_unstemmed | Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit |
| title_short | Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit |
| title_sort | hypotensive effect of achillea wilhelmsii aqueous ethanolic extract in rabbit |
| topic | Achillea wilhelmsii heart rate Blood pressure Rabbit |
| url | http://ajp.mums.ac.ir/pdf_121_6021025c5bf914e80846032682916fec.html |
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