Repurposing in vitro approaches for screening anti-parasitic drugs against the brain-eating amoeba Naegleria fowleri

Repurposing in vitro approaches for screening anti-parasitic drugs against the brain-eating amoeba Naegleria fowleri

Naegleria fowleri is both a pathogenic and a free-living microbial eukaryote, responsible for the development of primary amoebic meningoencephalitis (PAM) in humans. PAM is a rapid, severe and fatal underestimated infectious disease, which has been reported in countries with warmer climates. The maj...

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Bibliographic Details
Main Authors: Rubén Martín-Escolano, Lyto Yiangou, Eleanna Kazana, Gary K. Robinson, Martin Michaelis, Anastasios D. Tsaousis
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Naegleria
Brain-eating amoeba
PAM
Drug screening
Drug repurposing
Online Access:http://www.sciencedirect.com/science/article/pii/S221132072100052X

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