The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
Abstract Objective To assess maternal serum levels of vitamin D in fetuses appropriate for gestational age (AGA), small for gestational age (SGA), and with fetal growth restriction (FGR) according to estimated fetal weight (EFW). Methods This cross-sectional study included 87 pregnant women betw...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
2021-12-01
|
Series: | Revista Brasileira de Ginecologia e Obstetrícia |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021001000743&tlng=en |
_version_ | 1819005393406263296 |
---|---|
author | Vivian Macedo Gomes Marçal Francisco Lázaro Pereira Sousa Silvia Daher Raquel Margiotte Grohmann Alberto Borges Peixoto Edward Araujo Júnior Luciano Marcondes Machado Nardozza |
author_facet | Vivian Macedo Gomes Marçal Francisco Lázaro Pereira Sousa Silvia Daher Raquel Margiotte Grohmann Alberto Borges Peixoto Edward Araujo Júnior Luciano Marcondes Machado Nardozza |
author_sort | Vivian Macedo Gomes Marçal |
collection | DOAJ |
description | Abstract Objective To assess maternal serum levels of vitamin D in fetuses appropriate for gestational age (AGA), small for gestational age (SGA), and with fetal growth restriction (FGR) according to estimated fetal weight (EFW). Methods This cross-sectional study included 87 pregnant women between 26 and 36 weeks of gestation: 38 in the AGA group, 24 in the SGA group, and 25 in the FGR group. Maternal serum vitamin D levels were assessed using the chemiluminescence method. The Fisher exact test was used to compare the results between the groups. Results The mean ± standard deviation (SD) of maternal age (years) and body mass index (kg/m2) in the AGA, SGA, and FGR groups were 25.26 8.40 / 26.57 ± 4.37; 25.04 ± 8.44 / 26.09 ± 3.94; and 25.48 ± 7.52 / 26.24 ± 4.66, respectively (p > 0.05). The maternal serum vitamin D levels (mean ± SD) of the AGA, SGA, and FGR groups were 22.47 ± 8.35 ng/mL, 24.80 ± 10.76 ng/mL, and 23.61 ± 9.98 ng/mL, respectively, but without significant differences between the groups (p = 0.672). Conclusion Maternal serum vitamin D levels did not present significant differences among pregnant women with AGA, SGA, or FGR fetuses between 26 and 36 weeks of gestation according to EFW. |
first_indexed | 2024-12-20T23:52:05Z |
format | Article |
id | doaj.art-7e85ee4212d34c2c8bd43138a29f4583 |
institution | Directory Open Access Journal |
issn | 0100-7203 |
language | English |
last_indexed | 2024-12-20T23:52:05Z |
publishDate | 2021-12-01 |
publisher | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
record_format | Article |
series | Revista Brasileira de Ginecologia e Obstetrícia |
spelling | doaj.art-7e85ee4212d34c2c8bd43138a29f45832022-12-21T19:22:49ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032021-12-01431074374810.1055/s-0041-1735158The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional StudyVivian Macedo Gomes Marçalhttps://orcid.org/0000-0002-7734-523XFrancisco Lázaro Pereira Sousahttps://orcid.org/0000-0003-0761-7700Silvia Daherhttps://orcid.org/0000-0001-5312-7804Raquel Margiotte Grohmannhttps://orcid.org/0000-0002-1155-8582Alberto Borges Peixotohttps://orcid.org/0000-0002-1655-3609Edward Araujo Júniorhttps://orcid.org/0000-0002-6145-2532Luciano Marcondes Machado Nardozzahttps://orcid.org/0000-0002-6196-7712Abstract Objective To assess maternal serum levels of vitamin D in fetuses appropriate for gestational age (AGA), small for gestational age (SGA), and with fetal growth restriction (FGR) according to estimated fetal weight (EFW). Methods This cross-sectional study included 87 pregnant women between 26 and 36 weeks of gestation: 38 in the AGA group, 24 in the SGA group, and 25 in the FGR group. Maternal serum vitamin D levels were assessed using the chemiluminescence method. The Fisher exact test was used to compare the results between the groups. Results The mean ± standard deviation (SD) of maternal age (years) and body mass index (kg/m2) in the AGA, SGA, and FGR groups were 25.26 8.40 / 26.57 ± 4.37; 25.04 ± 8.44 / 26.09 ± 3.94; and 25.48 ± 7.52 / 26.24 ± 4.66, respectively (p > 0.05). The maternal serum vitamin D levels (mean ± SD) of the AGA, SGA, and FGR groups were 22.47 ± 8.35 ng/mL, 24.80 ± 10.76 ng/mL, and 23.61 ± 9.98 ng/mL, respectively, but without significant differences between the groups (p = 0.672). Conclusion Maternal serum vitamin D levels did not present significant differences among pregnant women with AGA, SGA, or FGR fetuses between 26 and 36 weeks of gestation according to EFW.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021001000743&tlng=enpregnancymaternal serum levelsvitamin Dsmall for gestational agefetal growth restriction |
spellingShingle | Vivian Macedo Gomes Marçal Francisco Lázaro Pereira Sousa Silvia Daher Raquel Margiotte Grohmann Alberto Borges Peixoto Edward Araujo Júnior Luciano Marcondes Machado Nardozza The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study Revista Brasileira de Ginecologia e Obstetrícia pregnancy maternal serum levels vitamin D small for gestational age fetal growth restriction |
title | The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study |
title_full | The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study |
title_fullStr | The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study |
title_full_unstemmed | The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study |
title_short | The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study |
title_sort | assessment of vitamin d levels in pregnant women is not associated to fetal growth restriction a cross sectional study |
topic | pregnancy maternal serum levels vitamin D small for gestational age fetal growth restriction |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021001000743&tlng=en |
work_keys_str_mv | AT vivianmacedogomesmarcal theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT franciscolazaropereirasousa theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT silviadaher theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT raquelmargiottegrohmann theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT albertoborgespeixoto theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT edwardaraujojunior theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT lucianomarcondesmachadonardozza theassessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT vivianmacedogomesmarcal assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT franciscolazaropereirasousa assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT silviadaher assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT raquelmargiottegrohmann assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT albertoborgespeixoto assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT edwardaraujojunior assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy AT lucianomarcondesmachadonardozza assessmentofvitamindlevelsinpregnantwomenisnotassociatedtofetalgrowthrestrictionacrosssectionalstudy |