The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study

Abstract Objective To assess maternal serum levels of vitamin D in fetuses appropriate for gestational age (AGA), small for gestational age (SGA), and with fetal growth restriction (FGR) according to estimated fetal weight (EFW). Methods This cross-sectional study included 87 pregnant women betw...

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Main Authors: Vivian Macedo Gomes Marçal, Francisco Lázaro Pereira Sousa, Silvia Daher, Raquel Margiotte Grohmann, Alberto Borges Peixoto, Edward Araujo Júnior, Luciano Marcondes Machado Nardozza
Format: Article
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2021-12-01
Series:Revista Brasileira de Ginecologia e Obstetrícia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021001000743&tlng=en
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author Vivian Macedo Gomes Marçal
Francisco Lázaro Pereira Sousa
Silvia Daher
Raquel Margiotte Grohmann
Alberto Borges Peixoto
Edward Araujo Júnior
Luciano Marcondes Machado Nardozza
author_facet Vivian Macedo Gomes Marçal
Francisco Lázaro Pereira Sousa
Silvia Daher
Raquel Margiotte Grohmann
Alberto Borges Peixoto
Edward Araujo Júnior
Luciano Marcondes Machado Nardozza
author_sort Vivian Macedo Gomes Marçal
collection DOAJ
description Abstract Objective To assess maternal serum levels of vitamin D in fetuses appropriate for gestational age (AGA), small for gestational age (SGA), and with fetal growth restriction (FGR) according to estimated fetal weight (EFW). Methods This cross-sectional study included 87 pregnant women between 26 and 36 weeks of gestation: 38 in the AGA group, 24 in the SGA group, and 25 in the FGR group. Maternal serum vitamin D levels were assessed using the chemiluminescence method. The Fisher exact test was used to compare the results between the groups. Results The mean ± standard deviation (SD) of maternal age (years) and body mass index (kg/m2) in the AGA, SGA, and FGR groups were 25.26 8.40 / 26.57 ± 4.37; 25.04 ± 8.44 / 26.09 ± 3.94; and 25.48 ± 7.52 / 26.24 ± 4.66, respectively (p > 0.05). The maternal serum vitamin D levels (mean ± SD) of the AGA, SGA, and FGR groups were 22.47 ± 8.35 ng/mL, 24.80 ± 10.76 ng/mL, and 23.61 ± 9.98 ng/mL, respectively, but without significant differences between the groups (p = 0.672). Conclusion Maternal serum vitamin D levels did not present significant differences among pregnant women with AGA, SGA, or FGR fetuses between 26 and 36 weeks of gestation according to EFW.
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spelling doaj.art-7e85ee4212d34c2c8bd43138a29f45832022-12-21T19:22:49ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032021-12-01431074374810.1055/s-0041-1735158The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional StudyVivian Macedo Gomes Marçalhttps://orcid.org/0000-0002-7734-523XFrancisco Lázaro Pereira Sousahttps://orcid.org/0000-0003-0761-7700Silvia Daherhttps://orcid.org/0000-0001-5312-7804Raquel Margiotte Grohmannhttps://orcid.org/0000-0002-1155-8582Alberto Borges Peixotohttps://orcid.org/0000-0002-1655-3609Edward Araujo Júniorhttps://orcid.org/0000-0002-6145-2532Luciano Marcondes Machado Nardozzahttps://orcid.org/0000-0002-6196-7712Abstract Objective To assess maternal serum levels of vitamin D in fetuses appropriate for gestational age (AGA), small for gestational age (SGA), and with fetal growth restriction (FGR) according to estimated fetal weight (EFW). Methods This cross-sectional study included 87 pregnant women between 26 and 36 weeks of gestation: 38 in the AGA group, 24 in the SGA group, and 25 in the FGR group. Maternal serum vitamin D levels were assessed using the chemiluminescence method. The Fisher exact test was used to compare the results between the groups. Results The mean ± standard deviation (SD) of maternal age (years) and body mass index (kg/m2) in the AGA, SGA, and FGR groups were 25.26 8.40 / 26.57 ± 4.37; 25.04 ± 8.44 / 26.09 ± 3.94; and 25.48 ± 7.52 / 26.24 ± 4.66, respectively (p > 0.05). The maternal serum vitamin D levels (mean ± SD) of the AGA, SGA, and FGR groups were 22.47 ± 8.35 ng/mL, 24.80 ± 10.76 ng/mL, and 23.61 ± 9.98 ng/mL, respectively, but without significant differences between the groups (p = 0.672). Conclusion Maternal serum vitamin D levels did not present significant differences among pregnant women with AGA, SGA, or FGR fetuses between 26 and 36 weeks of gestation according to EFW.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021001000743&tlng=enpregnancymaternal serum levelsvitamin Dsmall for gestational agefetal growth restriction
spellingShingle Vivian Macedo Gomes Marçal
Francisco Lázaro Pereira Sousa
Silvia Daher
Raquel Margiotte Grohmann
Alberto Borges Peixoto
Edward Araujo Júnior
Luciano Marcondes Machado Nardozza
The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
Revista Brasileira de Ginecologia e Obstetrícia
pregnancy
maternal serum levels
vitamin D
small for gestational age
fetal growth restriction
title The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
title_full The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
title_fullStr The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
title_full_unstemmed The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
title_short The Assessment of Vitamin D Levels in Pregnant Women is not Associated to Fetal Growth Restriction: A Cross Sectional Study
title_sort assessment of vitamin d levels in pregnant women is not associated to fetal growth restriction a cross sectional study
topic pregnancy
maternal serum levels
vitamin D
small for gestational age
fetal growth restriction
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021001000743&tlng=en
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