Epidemiology of spider mite sensitivity: a meta-analysis and systematic review
Abstract Background Spider mites, including Tetranychus urticae, Panonychus citri, and Panonychus ulmi, are common pests in gardens, greenhouses, and orchards. Exposure, particularly occupational exposure, to these organisms may lead to the development of respiratory or contact allergies. However, t...
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| Format: | Article |
| Language: | English |
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Wiley
2018-06-01
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| Series: | Clinical and Translational Allergy |
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| Online Access: | http://link.springer.com/article/10.1186/s13601-018-0209-8 |
| _version_ | 1818581759302828032 |
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| author | Ying Zhou Haoyuan Jia Xuming Zhou Yubao Cui Jun Qian |
| author_facet | Ying Zhou Haoyuan Jia Xuming Zhou Yubao Cui Jun Qian |
| author_sort | Ying Zhou |
| collection | DOAJ |
| description | Abstract Background Spider mites, including Tetranychus urticae, Panonychus citri, and Panonychus ulmi, are common pests in gardens, greenhouses, and orchards. Exposure, particularly occupational exposure, to these organisms may lead to the development of respiratory or contact allergies. However, the prevalence of sensitivity to spider mites is unclear. Methods We examined the literature to generate an estimate of the global prevalence of allergies to spider mites. Results Electronic databases were searched and twenty-three studies reporting the prevalence of sensitivity to spider mites (based on skin prick tests or IgE-based detection systems) in an aggregate total of 40,908 subjects were selected for analysis. The estimated overall rate of spider mite sensitivity was 22.9% (95% CI 19–26.8%). Heterogeneity was high and meta-regression analysis considering variables such as published year, country, number of study subjects, methods for allergen detection (skin prick test, ImmunoCAP, RAST testing, or intradermal test), and mite species revealed no single significant source. Twelve of the 23 studies reported rates of monosensitization (i.e., patients responsive to spider mites but no other tested allergen), yielding a global average of 7% (95% CI 5–9%), hence spider mites represent a unique source of allergens. Conclusions Spider mites are an important cause of allergic symptoms. However, the publication bias and heterogeneity evident in this study indicate that further trials using standardized detection methods are needed to determine the association of exposure and symptoms as well as the specific patient characteristics that influence developing spider mite sensitivity. |
| first_indexed | 2024-12-16T07:38:36Z |
| format | Article |
| id | doaj.art-7e885852df484eea89d52c8fd77adb3a |
| institution | Directory Open Access Journal |
| issn | 2045-7022 |
| language | English |
| last_indexed | 2024-12-16T07:38:36Z |
| publishDate | 2018-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Allergy |
| spelling | doaj.art-7e885852df484eea89d52c8fd77adb3a2022-12-21T22:39:08ZengWileyClinical and Translational Allergy2045-70222018-06-018111010.1186/s13601-018-0209-8Epidemiology of spider mite sensitivity: a meta-analysis and systematic reviewYing Zhou0Haoyuan Jia1Xuming Zhou2Yubao Cui3Jun Qian4Department of Pediatrics Laboratory, Wuxi Children’s HospitalDepartment of Clinical Laboratory, Wuxi People’s Hospital Affiliated to Nanjing Medical UniversityDepartment of Clinical Laboratory, Wuxi People’s Hospital Affiliated to Nanjing Medical UniversityDepartment of Clinical Laboratory, Wuxi People’s Hospital Affiliated to Nanjing Medical UniversityDepartment of Pediatrics, Wuxi Children’s HospitalAbstract Background Spider mites, including Tetranychus urticae, Panonychus citri, and Panonychus ulmi, are common pests in gardens, greenhouses, and orchards. Exposure, particularly occupational exposure, to these organisms may lead to the development of respiratory or contact allergies. However, the prevalence of sensitivity to spider mites is unclear. Methods We examined the literature to generate an estimate of the global prevalence of allergies to spider mites. Results Electronic databases were searched and twenty-three studies reporting the prevalence of sensitivity to spider mites (based on skin prick tests or IgE-based detection systems) in an aggregate total of 40,908 subjects were selected for analysis. The estimated overall rate of spider mite sensitivity was 22.9% (95% CI 19–26.8%). Heterogeneity was high and meta-regression analysis considering variables such as published year, country, number of study subjects, methods for allergen detection (skin prick test, ImmunoCAP, RAST testing, or intradermal test), and mite species revealed no single significant source. Twelve of the 23 studies reported rates of monosensitization (i.e., patients responsive to spider mites but no other tested allergen), yielding a global average of 7% (95% CI 5–9%), hence spider mites represent a unique source of allergens. Conclusions Spider mites are an important cause of allergic symptoms. However, the publication bias and heterogeneity evident in this study indicate that further trials using standardized detection methods are needed to determine the association of exposure and symptoms as well as the specific patient characteristics that influence developing spider mite sensitivity.http://link.springer.com/article/10.1186/s13601-018-0209-8AllergySpider mitesTetranychus urticaePanonychus citriPanonychus ulmi |
| spellingShingle | Ying Zhou Haoyuan Jia Xuming Zhou Yubao Cui Jun Qian Epidemiology of spider mite sensitivity: a meta-analysis and systematic review Clinical and Translational Allergy Allergy Spider mites Tetranychus urticae Panonychus citri Panonychus ulmi |
| title | Epidemiology of spider mite sensitivity: a meta-analysis and systematic review |
| title_full | Epidemiology of spider mite sensitivity: a meta-analysis and systematic review |
| title_fullStr | Epidemiology of spider mite sensitivity: a meta-analysis and systematic review |
| title_full_unstemmed | Epidemiology of spider mite sensitivity: a meta-analysis and systematic review |
| title_short | Epidemiology of spider mite sensitivity: a meta-analysis and systematic review |
| title_sort | epidemiology of spider mite sensitivity a meta analysis and systematic review |
| topic | Allergy Spider mites Tetranychus urticae Panonychus citri Panonychus ulmi |
| url | http://link.springer.com/article/10.1186/s13601-018-0209-8 |
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