Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses

Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses

Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of recombinant rotavirus vaccine. In our previous s...

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Bibliographic Details
Main Authors: Guoxing Luo, Yuanjun Zeng, Han Yang, Yijian Li, Lianwei Yang, Cao Li, Feibo Song, Shiyin Zhang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Biological sciences
Microbiology
Virology
Viral microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222013712

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